尼曼-匹克C蛋白在固醇转运与吸收中的作用：美中不足
Niemann-Pick C proteins in sterol transport and absorption: flies in the ointment.
作者信息
Ioannou Yiannis A
机构信息
Department of Genetics and Genomic Sciences, Box 1498, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA.
出版信息
Dev Cell. 2007 Apr;12(4):481-3. doi: 10.1016/j.devcel.2007.03.017.
PMID:17419988
Abstract
The Niemann-Pick C proteins have slowly emerged as regulators of subcellular lipid transport and sterol absorption at the small intestine. A recent article in Cell Metabolism suggests that in addition to their significant structural and sequence homology, these proteins may orchestrate their functions in a previously unappreciated fashion (Voght et al., 2007).
摘要
尼曼-皮克C蛋白已逐渐成为亚细胞脂质转运和小肠胆固醇吸收的调节因子。《细胞代谢》最近发表的一篇文章表明，除了具有显著的结构和序列同源性外，这些蛋白质可能以一种前所未有的方式协调其功能（Voght等人，2007年）。
Zotero 插件