在印度、俄罗斯和美国分离出的携带blaVIM-2的整合子源自一个早于3'保守序列形成的祖先1类整合子。
blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3' conserved sequence.
作者信息
Toleman Mark A, Vinodh Hemalatha, Sekar Uma, Kamat Vijaylakshmi, Walsh Timothy R
机构信息
Department of Medical Microbiology, University of Cardiff, Heath Park, Cardiff CF14 4XN, United Kingdom.
出版信息
Antimicrob Agents Chemother. 2007 Jul;51(7):2636-8. doi: 10.1128/AAC.01043-06. Epub 2007 Apr 16.
Abstract
The metallo-beta-lactamase gene bla(VIM-2) was identified in a strain of Pseudomonas aeruginosa isolated in India. The integron encoding bla(VIM-2) was virtually identical to those recently found in the United States and Russia. These unusual structures are likely to have arisen from an ancestral integron predating the formation of the 3' conserved sequence.
摘要
在印度分离出的一株铜绿假单胞菌中鉴定出金属β-内酰胺酶基因bla(VIM-2)。编码bla(VIM-2)的整合子与最近在美国和俄罗斯发现的整合子几乎相同。这些不同寻常的结构可能源自3'保守序列形成之前的一个祖先整合子。
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