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StructureViz:连接Cytoscape和UCSF Chimera

structureViz: linking Cytoscape and UCSF Chimera.

作者信息

Morris John H, Huang Conrad C, Babbitt Patricia C, Ferrin Thomas E

机构信息

Department of Pharmaceutical Chemistry, University of California, San Francisco, USA.

出版信息

Bioinformatics. 2007 Sep 1;23(17):2345-7. doi: 10.1093/bioinformatics/btm329. Epub 2007 Jul 10.

Abstract

structureViz is a Cytoscape plug-in that links the visualization of biological networks provided by Cytoscape with the visualization and analysis of macromolecular structures and sequences provided by UCSF Chimera. When combined with Cytoscape and Chimera, structureViz provides the first tool that links these two critical aspects of computational analysis in a straightforward manner. structureViz includes commands to open structures in Chimera and align them using Chimera's sequence-structure analysis tools. When a structure is opened, structureViz provides an alternative interface to Chimera: the Cytoscape Molecular Structure Navigator. This interface uses a tree-based paradigm to allow users to select and affect the display of models, chains and residues, mostly through the use of context menus.

摘要

StructureViz是一款Cytoscape插件,它将Cytoscape提供的生物网络可视化与加州大学旧金山分校(UCSF)Chimera提供的大分子结构和序列的可视化及分析联系起来。当与Cytoscape和Chimera结合使用时,StructureViz提供了首个能以直接方式将计算分析的这两个关键方面联系起来的工具。StructureViz包含在Chimera中打开结构并使用Chimera的序列-结构分析工具进行比对的命令。当打开一个结构时,StructureViz会为Chimera提供一个替代界面:Cytoscape分子结构导航器。该界面使用基于树的范式,让用户主要通过使用上下文菜单来选择并影响模型、链和残基的显示。

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