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希腊耐甲氧西林金黄色葡萄球菌中携带杀白细胞素基因和葡萄球菌盒式染色体mec V型的新克隆的出现。

Emergence of a new clone carrying Panton-Valentine leukocidin genes and staphylococcal cassette chromosome mec type V among methicillin-resistant Staphylococcus aureus in Greece.

作者信息

Chini Vassiliki, Petinaki Efthimia, Meugnier Héléne, Foka Antigoni, Bes Michele, Etienne Jerome, Dimitracopoulos George, Spiliopoulou Iris

机构信息

Department of Microbiology, School of Medicine, University of Patras, Patras, Greece.

出版信息

Scand J Infect Dis. 2008;40(5):368-72. doi: 10.1080/00365540701749230.

Abstract

Clonal analysis and PCR screening for the presence of Panton-Valentine leukocidin (PVL) genes was performed among 694 methicillin-resistant Staphylococcus aureus (MRSA) cases collected during a 2-y period in Greece. The detection rate of PVL-positive MRSA is high, both in the community and in hospital. Clonal analysis revealed the predominance among the PVL-positive strains of the clonal complex CC80 (ST80-IV) and the emergence of ST377 clone carrying agr1 allele and SCCmec type V.

摘要

在希腊为期2年的时间里收集的694例耐甲氧西林金黄色葡萄球菌(MRSA)病例中,进行了克隆分析和PCR筛选以检测是否存在杀白细胞素(PVL)基因。PVL阳性MRSA在社区和医院中的检出率都很高。克隆分析显示,克隆复合体CC80(ST80-IV)在PVL阳性菌株中占主导地位,并且出现了携带agr1等位基因和SCCmec V型的ST377克隆。

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