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季节性流感疫苗在美洲的推广。

Expansion of seasonal influenza vaccination in the Americas.

机构信息

Comprehensive Family Immunization Project, Pan American Health Organization, 525 Twenty Third St,, NW, Washington DC 20037-2895, USA.

出版信息

BMC Public Health. 2009 Sep 24;9:361. doi: 10.1186/1471-2458-9-361.

Abstract

BACKGROUND

Seasonal influenza is a viral disease whose annual epidemics are estimated to cause three to five million cases of severe illness and 250,000 to 500,000 deaths worldwide. Vaccination is the main strategy for primary prevention.

METHODS

To assess the status of influenza vaccination in the Americas, influenza vaccination data reported to the Pan American Health Organization (PAHO) through 2008 were analyzed.

RESULTS

Thirty-five countries and territories administered influenza vaccine in their public health sector, compared to 13 countries in 2004. Targeted risk groups varied. Sixteen countries reported coverage among older adults, ranging from 21% to 100%; coverage data were not available for most countries and targeted populations. Some tropical countries used the Northern Hemisphere vaccine formulation and others used the Southern Hemisphere vaccine formulation. In 2008, approximately 166.3 million doses of seasonal influenza vaccine were purchased in the Americas; 30 of 35 countries procured their vaccine through PAHO's Revolving Fund.

CONCLUSION

Since 2004 there has been rapid uptake of seasonal influenza vaccine in the Americas. Challenges to fully implement influenza vaccination remain, including difficulties measuring coverage rates, variable vaccine uptake, and limited surveillance and effectiveness data to guide decisions regarding vaccine formulation and timing, especially in tropical countries.

摘要

背景

季节性流感是一种病毒性疾病,其每年的流行估计在全球范围内导致 300 万至 500 万例重症病例和 25 万至 50 万人死亡。疫苗接种是主要的初级预防策略。

方法

为评估美洲的流感疫苗接种状况,对通过 2008 年向泛美卫生组织(PAHO)报告的流感疫苗接种数据进行了分析。

结果

与 2004 年的 13 个国家相比,35 个国家和地区在公共卫生部门接种了流感疫苗。目标风险群体有所不同。16 个国家报告了老年人的覆盖率,范围为 21%至 100%;大多数国家和目标人群都没有覆盖率数据。一些热带国家使用北半球的疫苗配方,而其他国家使用南半球的疫苗配方。2008 年,美洲购买了约 1.663 亿剂季节性流感疫苗;35 个国家中的 30 个通过 PAHO 的循环基金采购了疫苗。

结论

自 2004 年以来,季节性流感疫苗在美洲的接种率迅速上升。在全面实施流感疫苗接种方面仍然存在挑战,包括难以衡量覆盖率、疫苗接种率的差异以及有限的监测和效果数据,这些都难以指导疫苗配方和时间安排的决策,尤其是在热带国家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d688/2764707/6c09597ec933/1471-2458-9-361-1.jpg

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