Mayo Vaccine Research Group, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Mayo Clin Proc. 2010 Jan;85(1):64-76. doi: 10.4065/mcp.2009.0588. Epub 2009 Dec 10.
Within 2 months of its discovery last spring, a novel influenza A (H1N1) virus, currently referred to as 2009 H1N1, caused the first influenza pandemic in decades. The virus has caused disproportionate disease among young people with early reports of virulence similar to that of seasonal influenza. This clinical review provides an update encompassing the virology, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of the 2009 H1N1 virus. Because information about this virus, its prevention, and treatment are rapidly evolving, readers are advised to seek additional information. We performed a literature search of PubMed using the following keywords: H1N1, influenza, vaccine, pregnancy, children, treatment, epidemiology, and review. Studies were selected for inclusion in this review on the basis of their relevance. Recent studies and articles were preferred.
在去年春天发现新型甲型流感(H1N1)病毒后的 2 个月内,该病毒已引发了数十年来的首次流感大流行。目前该病毒已导致大量年轻人患病,其早期的毒性与季节性流感类似。本临床综述提供了有关该病毒的病毒学、流行病学、临床表现、诊断、治疗和预防的最新信息。由于有关该病毒、其预防和治疗的信息正在迅速发展,建议读者查阅更多信息。我们使用以下关键字在 PubMed 上进行了文献检索:H1N1、流感、疫苗、妊娠、儿童、治疗、流行病学和综述。本综述纳入的研究是基于其相关性选择的。优先选择了最近的研究和文章。