1 型糖尿病的 DCCT 和 EDIC 研究：代谢记忆和自然史对糖尿病神经病变的启示。
DCCT and EDIC studies in type 1 diabetes: lessons for diabetic neuropathy regarding metabolic memory and natural history.
机构信息
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
出版信息
Curr Diab Rep. 2010 Aug;10(4):276-82. doi: 10.1007/s11892-010-0120-8.
Abstract
The DCCT/EDIC (Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications) provides a comprehensive characterization of the natural history of diabetic neuropathy in patients with type 1 diabetes and provides insight into the impact of intensive insulin therapy in disease progression. The lessons learned about the natural history of distal symmetrical polyneuropathy and cardiovascular autonomic neuropathy and the impact of glycemic control on neuropathy are discussed in this review.
摘要
DCCT/EDIC（糖尿病控制和并发症试验/糖尿病干预和并发症的流行病学）全面描述了 1 型糖尿病患者糖尿病神经病变的自然病程，并深入了解了强化胰岛素治疗对疾病进展的影响。本文讨论了关于远端对称性多发性神经病和心血管自主神经病的自然病程以及血糖控制对神经病变影响的经验教训。
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本文引用的文献
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Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) Study.
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