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围手术期血流动力学治疗。

Perioperative haemodynamic therapy.

机构信息

Department of Anaesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russia.

出版信息

Curr Opin Crit Care. 2010 Aug;16(4):384-92. doi: 10.1097/MCC.0b013e32833ab81e.

Abstract

PURPOSE OF REVIEW

To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients.

RECENT FINDINGS

The choice of perioperative haemodynamic monitoring for GDT depends on the surgery-related and the patient-related risk. Conventional monitoring and minimally invasive approaches can be used for perioperative optimization of low-risk to moderate-risk patients. Thermodilution methods and continuous cardiac output/oxygen transport monitoring are the most reliable techniques for major surgery and high-risk/unstable patients. An important goal of perioperative haemodynamic therapy is to maintain cardiac function and organ perfusion, optimizing the balance between oxygen delivery and consumption. Several studies, using different monitoring tools and end-points, have shown that GDT provides optimal haemodynamic performance, improves organ function, reduces the number of complications and time to ICU and hospital discharge and decreases the mortality rate in high-risk surgical patients.

SUMMARY

GDT provides a number of benefits in major surgery. Based on adequate monitoring, the goal-directed algorithms facilitate early detection of pathophysiological changes and influence the perioperative haemodynamic therapy that can improve the clinical outcome. The perioperative GDT should be early, adequate and individualized for every patient.

摘要

目的综述

讨论围术期血流动力学监测工具和目标,评估目标导向治疗(GDT)对不同类别的手术患者的器官功能、并发症和结局的影响。

最近的发现

围术期 GDT 的血流动力学监测选择取决于与手术相关的和与患者相关的风险。传统监测和微创方法可用于低风险至中度风险患者的围术期优化。热稀释法和连续心输出量/氧运输监测是大手术和高风险/不稳定患者最可靠的技术。围术期血流动力学治疗的一个重要目标是维持心脏功能和器官灌注,优化氧输送与消耗之间的平衡。几项使用不同监测工具和终点的研究表明,GDT 可提供最佳的血流动力学性能,改善器官功能,减少并发症的数量,缩短 ICU 和住院时间,降低高危手术患者的死亡率。

总结

GDT 在大手术中提供了许多益处。基于充分的监测,目标导向算法有助于早期发现病理生理变化,并影响围术期血流动力学治疗,从而改善临床结局。围术期 GDT 应针对每个患者进行早期、充分和个体化。

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