Hulo Chantal, de Castro Edouard, Masson Patrick, Bougueleret Lydie, Bairoch Amos, Xenarios Ioannis, Le Mercier Philippe
Swiss-Prot group, Swiss Institute of Bioinformatics, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
Nucleic Acids Res. 2011 Jan;39(Database issue):D576-82. doi: 10.1093/nar/gkq901. Epub 2010 Oct 14.
The molecular diversity of viruses complicates the interpretation of viral genomic and proteomic data. To make sense of viral gene functions, investigators must be familiar with the virus host range, replication cycle and virion structure. Our aim is to provide a comprehensive resource bridging together textbook knowledge with genomic and proteomic sequences. ViralZone web resource (www.expasy.org/viralzone/) provides fact sheets on all known virus families/genera with easy access to sequence data. A selection of reference strains (RefStrain) provides annotated standards to circumvent the exponential increase of virus sequences. Moreover ViralZone offers a complete set of detailed and accurate virion pictures.
病毒的分子多样性使病毒基因组和蛋白质组数据的解读变得复杂。为了理解病毒基因的功能,研究人员必须熟悉病毒的宿主范围、复制周期和病毒粒子结构。我们的目标是提供一个全面的资源,将教科书知识与基因组和蛋白质组序列联系起来。ViralZone网络资源(www.expasy.org/viralzone/)提供了所有已知病毒科/属的情况说明书,便于获取序列数据。一系列参考菌株(RefStrain)提供了注释标准,以应对病毒序列呈指数级增长的情况。此外,ViralZone还提供了一整套详细准确的病毒粒子图片。