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超声引导(针在平面内)经皮神经导管置入术:导管置入距离对术后镇痛的影响。

Ultrasound-guided (needle-in-plane) perineural catheter insertion: the effect of catheter-insertion distance on postoperative analgesia.

机构信息

Department of Anesthesiology, University of California, San Diego, CA, USA.

出版信息

Reg Anesth Pain Med. 2011 May-Jun;36(3):261-5. doi: 10.1097/AAP.0b013e31820f3b80.

Abstract

BACKGROUND

When using ultrasound guidance to place a perineural catheter for a continuous peripheral nerve block, keeping the needle in plane and nerve in short axis results in a perpendicular needle-to-nerve orientation. Many have opined that when placing a perineural catheter via the needle, the acute angle may result in the catheter bypassing the target nerve when advanced beyond the needle tip. Theoretically, greater catheter tip-to-nerve distances result in less local anesthetic-to-nerve contact during the subsequent perineural infusion, leading to inferior analgesia. Although a potential solution may appear obvious-advancing the catheter tip only to the tip of the needle, leaving the catheter tip at the target nerve-this technique has not been prospectively evaluated. We therefore hypothesized that during needle in-plane ultrasound-guided perineural catheter placement, inserting the catheter a minimum distance (0-1 cm) past the needle tip is associated with improved postoperative analgesia compared with inserting the catheter a more traditional 5 to 6 cm past the needle tip.

METHODS

Preoperatively, subjects received a popliteal-sciatic perineural catheter for foot or ankle surgery using ultrasound guidance exclusively. Subjects were randomly assigned to have a single-orifice, flexible catheter inserted either 0 to 1 cm (n = 50) or 5 to 6 cm (n = 50) past the needle tip. All subjects received a single-injection mepivacaine (40 mL of 1.5% with epinephrine) nerve block via the needle, followed by catheter insertion and a ropivacaine 0.2% infusion (basal 6 mL/hr, bolus 4 mL, 30-min lockout), through at least the day after surgery. The primary end point was the average surgical pain as measured with a 0- to 10-point numeric rating scale the day after surgery. Secondary end points included time for catheter insertion, incidence of catheter dislodgement, maximum ("worst") pain scores, opioid requirements, fluid leakage at the catheter site, and the subjective degree of an insensate extremity.

RESULTS

Average pain scores the day after surgery for subjects of the 0- to 1-cm group were a median of 2.5 (interquartile range, 0.0-5.0), compared with 2.0 (interquartile range, 0.0-4.0) for subjects of the 5- to 6-cm group (P = 0.42). Similarly, among the secondary end points, no statistically significant differences were found between the 2 treatment groups. There was a trend of more catheter dislodgements in the minimum-insertion group (5 vs 1; P = 0.20).

CONCLUSIONS

This study did not find evidence to support the hypothesis that, for popliteal-sciatic perineural catheters placed using ultrasound guidance and a needle-in-plane technique, inserting the catheter a minimum distance (0-1 cm) past the needle tip improves (or worsens) postoperative analgesia compared with inserting the catheter a more traditional distance (5-6 cm). Caution is warranted if extrapolating these results to other catheter designs, ultrasound approaches, or anatomic insertion sites.

摘要

背景

在使用超声引导进行连续外周神经阻滞时,将针保持在平面内并使神经处于短轴方向,可使针与神经呈垂直方向。许多人认为,当通过针放置外周神经导管时,锐角可能导致导管在针尖超出后绕过目标神经。理论上,导管尖端与神经之间的距离越大,在随后的神经周围输注过程中,局部麻醉剂与神经的接触就越少,从而导致镇痛效果不佳。尽管一个潜在的解决方案似乎显而易见-将导管尖端推进至针尖端,仅将导管尖端留在目标神经上-但这种技术尚未经过前瞻性评估。因此,我们假设在针在平面内超声引导下进行外周神经导管放置时,将导管插入针尖端后最小距离(0-1cm)与将导管插入传统的 5-6cm 后相比,可改善术后镇痛效果超过针尖端。

方法

术前,受试者接受了单独使用超声引导的用于足部或踝关节手术的隐窝-坐骨神经外周神经导管。受试者被随机分配到单孔,柔性导管插入针尖端后 0-1cm(n=50)或 5-6cm(n=50)处。所有受试者均接受单次注射甲哌卡因(含肾上腺素的 1.5%40ml)神经阻滞,然后插入导管并进行罗哌卡因 0.2%输注(基础输注 6ml/hr,推注 4ml,30min 锁定),至少在手术后一天。主要终点是术后第一天使用 0-10 分数字评分法测量的平均手术疼痛。次要终点包括导管插入时间,导管脱位发生率,最大(“最严重”)疼痛评分,阿片类药物需求,导管部位漏液以及感觉迟钝的主观程度。

结果

0-1cm 组术后第一天的平均疼痛评分中位数为 2.5(四分位间距,0.0-5.0),而 5-6cm 组为 2.0(四分位间距,0.0-4.0)(P=0.42)。同样,在次要终点中,两组之间也没有发现统计学上的显著差异。在最小插入组中,导管脱位的发生率呈上升趋势(5 比 1;P=0.20)。

结论

本研究没有证据支持以下假设:对于使用超声引导和针在平面内技术放置的隐窝-坐骨神经外周神经导管,将导管插入针尖端后最小距离(0-1cm)可改善(或恶化)与插入导管传统距离(5-6cm)相比,术后镇痛效果。如果将这些结果推断到其他导管设计,超声方法或解剖插入部位,则需要谨慎。

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