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重新组织通用蛋白质资源库(UniProt)中的蛋白质空间。

Reorganizing the protein space at the Universal Protein Resource (UniProt).

机构信息

The EMBL Outstation, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Nucleic Acids Res. 2012 Jan;40(Database issue):D71-5. doi: 10.1093/nar/gkr981. Epub 2011 Nov 18.

Abstract

The mission of UniProt is to support biological research by providing a freely accessible, stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and querying interfaces. UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. A key development at UniProt is the provision of complete, reference and representative proteomes. UniProt is updated and distributed every 4 weeks and can be accessed online for searches or download at http://www.uniprot.org.

摘要

UniProt 的使命是通过提供免费访问、稳定、全面、完全分类、丰富且准确注释的蛋白质序列知识库,以及广泛的交叉引用和查询界面,来支持生物研究。UniProt 由四个主要部分组成,每个部分都针对不同的用途进行了优化:UniProt 档案、UniProt 知识库、UniProt 参考簇和 UniProt 宏基因组和环境序列数据库。UniProt 的一个重要发展是提供完整的、参考的和有代表性的蛋白质组。UniProt 每 4 周更新一次,并分发一次,可在线访问进行搜索,或在 http://www.uniprot.org 下载。

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