Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
J Nutr Health Aging. 2012 Jan;16(1):89-98. doi: 10.1007/s12603-011-0073-x.
Obesity is a risk factor for chronic diseases and premature mortality, but the extent of these associations among the elderly is under debate. The aim of this systematic literature review (SR) is to collate and critically assess the available information of the impact of obesity on mortality in the elderly.
In PubMed, there are three-hundred twelve papers on the relationship between obesity and mortality among older adults. These papers were analysed on the basis of their abstracts, and sixteen studies were considered suitable for the purpose of the study. It was possible to perform a pooled estimate for aggregated data in three different studies.
The results of this SR document that an increased mortality in obese older adults. The limitation of BMI to index obesity and the noted protective action of a moderate increase in BMI on mortality are highlighted. Waist circumference is an indicator of central adiposity and potentially as good a risk factor for mortality as BMI in obese elderly adults.
肥胖是慢性病和早逝的一个风险因素,但老年人中这些关联的程度仍存在争议。本系统文献综述(SR)的目的是整理和批判性评估肥胖对老年人死亡率影响的现有信息。
在 PubMed 中,有 312 篇关于肥胖与老年人死亡率之间关系的论文。根据这些论文的摘要进行了分析,并认为有 16 项研究适合本研究的目的。在三项不同的研究中,可以对汇总数据进行汇总估计。
本 SR 的结果表明,肥胖的老年人群死亡率增加。强调了 BMI 作为肥胖指标的局限性以及 BMI 适度增加对死亡率的保护作用。腰围是中心性肥胖的一个指标,在肥胖的老年人群中,它可能是与死亡率一样好的风险因素。