蛋白质相互作用数据编纂：国际分子交换（IMEx）联盟。
Protein interaction data curation: the International Molecular Exchange (IMEx) consortium.
机构信息
European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK.
出版信息
Nat Methods. 2012 Apr;9(4):345-50. doi: 10.1038/nmeth.1931.
Abstract
The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website (http://www.imexconsortium.org/). Common curation rules have been developed, and a central registry is used to manage the selection of articles to enter into the dataset. We discuss the advantages of such a service to the user, our quality-control measures and our data-distribution practices.
摘要
国际分子交换（IMEx）联盟是一个国际性的合作组织，由主要的公共交互数据提供者组成，旨在共享文献整理工作，并在一个共同的网站（http://www.imexconsortium.org/）上提供一个单一的搜索界面，其中包含一个非冗余的蛋白质相互作用数据集。已经制定了共同的整理规则，并使用一个中央注册表来管理要进入数据集的文章选择。我们讨论了这种服务对用户的优势、我们的质量控制措施以及我们的数据分发实践。
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本文引用的文献
1
PSICQUIC and PSISCORE: accessing and scoring molecular interactions.
Nat Methods. 2011 Jun 29;8(7):528-9. doi: 10.1038/nmeth.1637.
2
Literature curation of protein interactions: measuring agreement across major public databases.
Database (Oxford). 2010 Dec 22;2010:baq026. doi: 10.1093/database/baq026. Print 2010.
3
Ongoing and future developments at the Universal Protein Resource.
Nucleic Acids Res. 2011 Jan;39(Database issue):D214-9. doi: 10.1093/nar/gkq1020. Epub 2010 Nov 4.
4
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored.
Nucleic Acids Res. 2011 Jan;39(Database issue):D561-8. doi: 10.1093/nar/gkq973. Epub 2010 Nov 2.
5
iRefWeb: interactive analysis of consolidated protein interaction data and their supporting evidence.
Database (Oxford). 2010 Oct 12;2010:baq023. doi: 10.1093/database/baq023.
6
MatrixDB, the extracellular matrix interaction database.
Nucleic Acids Res. 2011 Jan;39(Database issue):D235-40. doi: 10.1093/nar/gkq830. Epub 2010 Sep 17.
7
The FEBS Letters/BioCreative II.5 experiment: making biological information accessible.
Nat Biotechnol. 2010 Sep;28(9):897-9. doi: 10.1038/nbt0910-897.
8
Exhaustive benchmarking of the yeast two-hybrid system.
Nat Methods. 2010 Sep;7(9):667-8; author reply 668. doi: 10.1038/nmeth0910-667.
9
A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease.
Proteomics. 2010 Jun;10(12):2377-95. doi: 10.1002/pmic.200900773.
10
Recurated protein interaction datasets.
Nat Methods. 2009 Dec;6(12):860-1. doi: 10.1038/nmeth1209-860.
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