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腹腔镜袖状胃切除术与腹腔镜可调节胃束带术治疗高危患者的重度肥胖症

Laparoscopic sleeve gastrectomy versus laparoscopic adjustable gastric banding for the treatment severe obesity in high risk patients.

作者信息

Varela J Esteban

机构信息

Department of Surgery, Washington University, St. Louis, MO, USA.

出版信息

JSLS. 2011 Oct-Dec;15(4):486-91. doi: 10.4293/108680811X13176.

Abstract

BACKGROUND

Laparoscopic sleeve gastrectomy (LSG) has emerged as an alternative restrictive bariatric procedure to the most popular laparoscopic adjustable gastric banding (LAGB). We analyze and compare the clinical and weight loss outcomes of LSG versus LAGB for the treatment of severe obesity in high-risk patients.

METHODS

Forty severely obese veterans (20/group) received either LSG or LAGB and were followed prospectively for 2 years. Outcome measures included operating room (OR) time, estimated blood loss (EBL), length of hospital stay (LOS), morbidity, mortality, reoperations, readmission rates, and weight loss over time.

RESULTS

The cohort primarily comprised high-risk and older male veterans. Patient's baseline demographics were similar between groups. LSG was associated with prolonged OR time (116±31 vs. 94±28min), higher EBL (34±28 vs. 17±19mL), and LOS (2±.9 vs. 1±.4days) when compared with LAGB. Minor morbidity and readmissions were similar between groups, while no major morbidity, reoperations, or mortality occurred. Total weight and BMI decreased significantly after surgery in both groups (LSG: 302±52 to 237lbs and 45±5 to 36±5kg/m(2) vs. LAGB: 280±36 to 231±29lbs and 43±5 to 36±5kg/m(2), respectively). Total weight loss was superior in the LSG vs. LAGB group at 2 years (TWL=65±24 vs. 49±28 lbs (P=.03); %EWL=51±20 vs. 46±23%; %EBMI loss=48±22 vs. 45±23%, and %BWL=21±8 vs. 17±9%, respectively).

CONCLUSION

In severely obese and high-risk patients, laparoscopic sleeve gastrectomy provides superior total weight loss at 2 years.

摘要

背景

腹腔镜袖状胃切除术(LSG)已成为最流行的腹腔镜可调节胃束带术(LAGB)之外的另一种限制性减肥手术。我们分析并比较了LSG与LAGB治疗高危严重肥胖患者的临床及减重效果。

方法

40例严重肥胖退伍军人(每组20例)接受了LSG或LAGB手术,并进行了为期2年的前瞻性随访。观察指标包括手术时间(OR)、估计失血量(EBL)、住院时间(LOS)、发病率、死亡率、再次手术率、再入院率以及随时间的体重减轻情况。

结果

该队列主要由高危和老年男性退伍军人组成。两组患者的基线人口统计学特征相似。与LAGB相比,LSG与更长的手术时间(116±31对94±28分钟)、更高的失血量(34±28对17±19毫升)和住院时间(2±0.9对1±0.4天)相关。两组的轻微发病率和再入院率相似,未发生重大发病率、再次手术或死亡情况。两组患者术后总体重和BMI均显著下降(LSG组:从302±52磅降至237磅,从45±5降至36±5kg/m²;LAGB组:从280±36磅降至231±29磅,从43±5降至36±5kg/m²)。2年时,LSG组的总体重减轻优于LAGB组(TWL=65±24对49±28磅(P=0.03);%EWL=51±20对46±23%;%EBMI降低=48±22对45±23%,%BWL=21±8对17±9%)。

结论

在严重肥胖的高危患者中,腹腔镜袖状胃切除术在2年时能实现更优的总体重减轻。

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