Division of Respirology, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B IW8, Canada.
Can Respir J. 2012 May-Jun;19(3):e18-24. doi: 10.1155/2012/732618.
To estimate the prevalence and determine the risk factors and health associations among individuals with combined chronic obstructive pulmonary disease and obesity.
Canadian national health survey data from 1994 to 2007 (n=650,000) were used. The presence of COPD was based on health professional-diagnosed self-report. The presence of obesity, defined by body mass index ≥ 30 kg⁄m2, was identified using self-reported and measured height and weight. Hospitalization, homecare use, physical activity assessments and socioeconomic data were all self-reported.
In 2005, the prevalence of obesity in COPD (n=3470) and non-COPD (n=92,237) individuals was 24.6% and 17.1%, respectively (P<0.0001). In contrast to the non-COPD group, in which obesity prevalence increased by 38% over 14 years, obesity prevalence increased by only 5% in people with COPD over this same time period. Female sex was the only independent risk factor for obesity in COPD. Previous smoking, residing in Atlantic Canada and the Territories, and low education level were independent risk factors for obesity in the non-COPD group, but not in the COPD group. The odds of physical activity limitation and health care utilization were significantly higher among obese individuals with COPD compared with nonobese COPD and obese non-COPD groups.
The prevalence of obesity was higher in COPD, and exceeded that of the larger non-COPD group throughout the 13-year observation period. The presence of obesity in COPD was associated with significantly higher risk of severe activity limitation and increased health care utilization. The combination of obesity and COPD has major implications for health care delivery that has not been previously appreciated.
评估合并慢性阻塞性肺疾病和肥胖症患者的患病率,并确定其危险因素和健康关联。
利用 1994 年至 2007 年加拿大全国健康调查数据(n=650000)。通过健康专业人员诊断的自我报告确定 COPD 的存在。肥胖的存在通过自我报告和测量的身高和体重来确定,定义为体重指数≥30kg/m2。住院、家庭护理使用、身体活动评估和社会经济数据均为自我报告。
2005 年,COPD(n=3470)和非 COPD(n=92237)患者的肥胖患病率分别为 24.6%和 17.1%(P<0.0001)。与非 COPD 组相比,肥胖患病率在 14 年内增加了 38%,而 COPD 患者在同一时期仅增加了 5%。女性是 COPD 患者肥胖的唯一独立危险因素。既往吸烟、居住在大西洋省份和地区以及低教育水平是非 COPD 患者肥胖的独立危险因素,但不是 COPD 患者的危险因素。与非肥胖 COPD 患者和肥胖非 COPD 患者相比,COPD 肥胖患者身体活动受限和医疗保健利用的几率显著更高。
肥胖症在 COPD 中的患病率更高,在 13 年的观察期间,其患病率超过了更大的非 COPD 组。COPD 患者肥胖症与严重活动受限和更高的医疗保健利用率的风险显著增加有关。肥胖症和 COPD 的结合对以前未被重视的医疗保健提供方式具有重大影响。