[重庆企事业单位职工血浆脂质水平与血脂异常发病率]

Gao Ya, Zhong Xiao-ni, Yang Yan-hong, Tian Kao-cong

Department of Health Statistics, Chongqing Medical University, Chongqing, China.

Zhonghua Xin Xue Guan Bing Za Zhi. 2012 May;40(5):432-5.

OBJECTIVE

To examine the plasma lipid level and distribution of dyslipidemia in workers of Chongqing enterprises and institutions.

METHODS

By using cluster sampling method, 20 000 workers of Chongqing enterprises and institutions aged 18 to 60 were selected as target population from January to October, 2009. We conducted questionnaire survey, physical and laboratory examinations including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Workers were divided into 18 - 29 years old group, 30 - 39 years old group, 40 - 49 years old group and 50 - 60 years old group. Characteristic and distribution of dyslipidemia were analyzed.

RESULTS

Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were significantly different in various age group (all P < 0.01). TC, TG, HDL-C and LDL-C levels in the 30 years and over groups were all significantly higher than in the under 30 years old group(all P < 0.01). The TG levels in the 40 - 49 years old group and the 50 - 60 years old group were similar (P > 0.05). After adjusting for age, TC, TG, HDL-C and LDL-C levels in males were all significantly higher than in females (all P < 0.01). The incidence of dyslipidemia in this population was 35.01% and significantly higher in males than that of females (58.27% vs. 11.01%, P < 0.01). The incidence of dyslipidemia increased with aging (P < 0.01).

CONCLUSIONS

The prevalence of dyslipidemia is high in Chongqing enterprises and institutions. The incidence of dyslipidemia is higher in males than in females and higher among the 30 years and over workers than that of under 30 years old workers.

目的

调查重庆企事业单位职工血脂水平及血脂异常分布情况。

方法

采用整群抽样法，选取2009年1月至10月重庆企事业单位18至60岁的20000名职工作为研究对象。进行问卷调查、体格检查及实验室检查，包括总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）。将职工分为18 - 29岁组、30 - 39岁组、40 - 49岁组和50 - 60岁组，分析血脂异常的特点及分布情况。

结果

各年龄组总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）差异均有统计学意义（均P < 0.01）。30岁及以上组的TC、TG、HDL-C和LDL-C水平均显著高于30岁以下组（均P < 0.01）。40 - 49岁组与50 - 60岁组的TG水平相近（P > 0.05）。校正年龄后，男性的TC、TG、HDL-C和LDL-C水平均显著高于女性（均P < 0.01）。该人群血脂异常发生率为35.01%，男性显著高于女性（58.27%对11.01%，P < 0.01）。血脂异常发生率随年龄增长而升高（P < 0.01）。