IFIT2（ISG54）的晶体结构预测了 IFITs 的功能特性。
Crystal structure of IFIT2 (ISG54) predicts functional properties of IFITs.
机构信息
Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, OH 44195, USA.
出版信息
Cell Res. 2012 Oct;22(10):1407-9. doi: 10.1038/cr.2012.130. Epub 2012 Sep 11.
Abstract
Interferon carries out its cellular effects, including its antiviral effects, by inducing the synthesis of many new proteins, amongst which is the IFIT (ISG56) family of proteins. The first crystal structure of an IFIT, reported by Yang et al., revealed several functional properties of the protein that may help us to better understand the biological functions of these proteins.
摘要
干扰素通过诱导许多新蛋白的合成来发挥其细胞效应，包括抗病毒作用，其中包括 IFIT（ISG56）蛋白家族。Yang 等人报告的第一个 IFIT 的晶体结构揭示了该蛋白的几个功能特性，这可能有助于我们更好地理解这些蛋白的生物学功能。
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本文引用的文献
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