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持续隐神经阻滞作为单次局部浸润镇痛在全膝关节置换术后疼痛管理中的补充。

Continuous saphenous nerve block as supplement to single-dose local infiltration analgesia for postoperative pain management after total knee arthroplasty.

机构信息

Department of Anaesthesia, Copenhagen University Hospital, Frederiksberg, Denmark.

出版信息

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):106-11. doi: 10.1097/AAP.0b013e31827900a9.

Abstract

BACKGROUND AND OBJECTIVES

Local infiltration analgesia (LIA) reduces pain after total knee arthroplasty without the motor blockade associated with epidural analgesia or femoral nerve block. However, the duration and efficacy of LIA are not sufficient. A saphenous nerve block, in addition to single-dose LIA, may improve analgesia without interfering with early mobilization.

METHODS

Forty patients were included in this double-blind randomized controlled trial. All patients received spinal anesthesia for surgery and single-dose LIA during the operation. An ultrasound-guided saphenous nerve catheter was placed postoperatively in the adductor canal at midthigh level. Patients were randomized into 2 groups to receive 15-mL boluses of either ropivacaine 7.5 mg/mL or saline twice daily for 2 postoperative days.

RESULTS

Worst pain scores during movement on the day of surgery were significantly lower in the ropivacaine group (median [range] visual analog scale, 3 [0-7] vs 5.5 [0-10]; P < 0.050), as well as pain at rest (visual analog scale, 2 [0-8] vs 4 [0-8]; P = 0.032). Breakthrough pain occurred later in the ropivacaine group (10.5 [range, 0.5-48] hours vs 3.4 [range, 0.5-24] hours; P = 0.011). All patients in the ropivacaine group were able to ambulate on the day of surgery versus 13 patients in the control group (P = 0.004). Fewer patients had sleep disturbance on the first postoperative night in the ropivacaine group (P = 0.038). We found no differences in morphine consumption.

CONCLUSIONS

The combination of a saphenous nerve block with single-dose LIA offered better pain relief on the day of surgery than LIA alone.

摘要

背景与目的

局部浸润镇痛(LIA)可减轻全膝关节置换术后的疼痛,且不会产生与硬膜外镇痛或股神经阻滞相关的运动阻滞。然而,LIA 的持续时间和效果并不足够。在单次 LIA 的基础上增加隐神经阻滞可能会改善镇痛效果,同时不影响早期活动。

方法

本双盲随机对照试验纳入了 40 名患者。所有患者在手术中均接受了脊髓麻醉和术中单次 LIA。术后在大腿中高位的收肌管内放置超声引导的隐神经导管。患者随机分为两组,术后 2 天内每天接受 2 次 15 mL 的罗哌卡因 7.5 mg/mL 或生理盐水推注。

结果

手术当天活动时的最差疼痛评分在罗哌卡因组显著降低(中位数[范围]视觉模拟评分,3[0-7] vs 5.5[0-10];P<0.050),休息时的疼痛也较低(视觉模拟评分,2[0-8] vs 4[0-8];P=0.032)。罗哌卡因组出现爆发性疼痛的时间较晚(10.5[范围,0.5-48]小时 vs 3.4[范围,0.5-24]小时;P=0.011)。与对照组相比,所有罗哌卡因组的患者在手术当天均能行走(P=0.004)。罗哌卡因组在术后第一晚睡眠障碍的患者较少(P=0.038)。我们未发现两组间吗啡消耗的差异。

结论

隐神经阻滞联合单次 LIA 比单独使用 LIA 在手术当天能提供更好的镇痛效果。

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