Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
Nat Methods. 2013 Sep;10(9):877-9. doi: 10.1038/nmeth.2560. Epub 2013 Jul 14.
Using low-cost automated tracking microscopes, we have generated a behavioral database for 305 Caenorhabditis elegans strains, including 76 mutants with no previously described phenotype. The growing database currently consists of 9,203 short videos segmented to extract behavior and morphology features, and these videos and feature data are available online for further analysis. The database also includes summary statistics for 702 measures with statistical comparisons to wild-type controls so that phenotypes can be identified and understood by users.
我们使用低成本的自动化跟踪显微镜,为 305 个秀丽隐杆线虫品系生成了一个行为数据库,其中包括 76 个以前没有描述过表型的突变体。这个不断增长的数据库目前包含 9203 个短视频,这些视频被分割以提取行为和形态特征,这些视频和特征数据可在线供进一步分析使用。该数据库还包括 702 个度量的汇总统计信息,并与野生型对照进行了统计比较,以便用户能够识别和理解表型。