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使用具有偏态T分布的贝叶斯多层次模型对伊朗聚丙烯公司工人血压影响因素的历史性队列研究。

Historical cohort study on the factors affecting blood pressure in workers of polyacryl iran corporation using bayesian multilevel modeling with skew T distribution.

作者信息

Gholami Fesharaki Mohammad, Kazemnejad Anoshirvan, Zayeri Farid, Sanati Javad, Akbari Hamed

机构信息

Biostatistics Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, IR Iran.

Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.

出版信息

Iran Red Crescent Med J. 2013 May;15(5):418-23. doi: 10.5812/ircmj.10930. Epub 2013 May 5.

Abstract

BACKGROUND

Hypertension is considered as a major public health problem in most countries due to its association with ischemic heart disease which causes cerebrovascular disease and death.

OBJECTIVES

The purpose of the present study was to study factors affecting Blood Pressure (BP).

PATIENTS AND METHODS

The data were extracted from annual observation of the workers who worked in Polyacryl Iran Corporation (PIC) between 1998 and 2010. In this research, we assessed the effect of Body Mass Index (BMI), age, sex, job status, marital status, job schedule type, and education level on Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) using Bayesian multilevel modeling with skew t distribution using WinBUGS software.

RESULTS

Totally 3965 persons participated in this study, 75(1.9%) female and 3890 (98.1%) male. In this study age, sex, BMI, job status, marital status, and education level had statistical association with SBP. The result for DBP was similar to SBP except the education level which had no statistical association.

CONCLUSIONS

Treating obesity, increasing physical activity and quality of married life are proposed as practical solutions to reduce BP.

摘要

背景

在大多数国家,高血压被视为一个主要的公共卫生问题,因为它与导致脑血管疾病和死亡的缺血性心脏病有关。

目的

本研究的目的是研究影响血压(BP)的因素。

患者与方法

数据取自1998年至2010年期间在伊朗聚丙烯公司(PIC)工作的员工的年度观察资料。在本研究中,我们使用WinBUGS软件,采用具有偏态t分布的贝叶斯多水平模型,评估体重指数(BMI)、年龄、性别、工作状态、婚姻状况、工作时间表类型和教育水平对收缩压(SBP)和舒张压(DBP)的影响。

结果

共有3965人参与本研究,其中女性75人(1.9%),男性3890人(98.1%)。在本研究中,年龄、性别、BMI、工作状态、婚姻状况和教育水平与SBP存在统计学关联。DBP的结果与SBP相似,只是教育水平无统计学关联。

结论

治疗肥胖、增加体育活动和提高婚姻生活质量被提议作为降低血压的实际解决方案。

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