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外周动脉疾病

Peripheral arterial disease.

作者信息

Mascarenhas Janice V, Albayati Mostafa A, Shearman Clifford P, Jude Edward B

机构信息

Department of Endocrinology, Tameside Hospital NHS Foundation Trust, Fountain Street, Ashton-Under-Lyne, Lancashire OL6 9RW, UK; University of Manchester, Oxford Road, Manchester M13 9PL, UK.

Department of Vascular Surgery, University Hospital Southampton NHS Foundation Trust, Southampton General Hospital, Tremona Road, Southampton, Hampshire SO16 6YD, UK.

出版信息

Endocrinol Metab Clin North Am. 2014 Mar;43(1):149-66. doi: 10.1016/j.ecl.2013.09.003.

Abstract

Peripheral arterial disease (PAD) is an atherosclerotic-driven condition that remains underdiagnosed and undertreated. In diabetic patients, PAD begins early, progresses rapidly, and is frequently asymptomatic, making it difficult to diagnose. Strict management of the metabolic instigators and use of screening techniques for PAD in diabetes can facilitate early diagnosis and reduce progression. Exercise is an equally effective treatment option in improving walking distance. Early revascularization must be offered early in suitable patients. Surgical bypass and endovascular revascularization are complementary and the choice of intervention should be applied appropriately by a multidisciplinary vascular team on a selective, patient-specific basis.

摘要

外周动脉疾病(PAD)是一种由动脉粥样硬化驱动的疾病,目前仍存在诊断不足和治疗不足的情况。在糖尿病患者中,PAD发病早、进展快,且常常没有症状,这使得诊断变得困难。对代谢诱因进行严格管理并在糖尿病患者中使用PAD筛查技术有助于早期诊断并减缓病情发展。运动在增加步行距离方面同样是一种有效的治疗选择。对于合适的患者应尽早进行早期血运重建。外科搭桥和血管腔内血运重建是相辅相成的,多学科血管团队应根据患者的具体情况,有选择地合理应用干预措施。

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