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精子机器人:对药物递送和辅助生殖技术的潜在影响。

Spermbots: potential impact for drug delivery and assisted reproductive technologies.

作者信息

Magdanz Veronika, Schmidt Oliver G

机构信息

Institute for Integrative Nanosciences, IFW Dresden , Helmholtzstraße 20, 01069 Dresden , Germany.

出版信息

Expert Opin Drug Deliv. 2014 Aug;11(8):1125-9. doi: 10.1517/17425247.2014.924502. Epub 2014 May 31.

Abstract

Micromotors and nanomotors are an emerging research field that aims at achieving locomotion on the microscale for a variety of applications such as drug delivery, single cell manipulation, microsensors and lab-on-a-chip devices, just to point out a few. The enthusiastic development of hybrid micromotors harnessing biological power sources for physiologically compatible nano/microdevices has recently brought a lot of attention to the international research community that is looking for a solution for the actuation and locomotion on the microscale. This article describes the potential of sperm-driven micro-bio-robots in the biomedical field such as drug delivery or single cell manipulation. Herein, a specific potential of the sperm-driven micro-bio-robot is described that might have impact on the development of assisted reproductive technologies.

摘要

微电机和纳米电机是一个新兴的研究领域,旨在实现微尺度下的运动,以用于多种应用,如药物递送、单细胞操作、微传感器和芯片实验室设备等等。利用生物能源的混合微电机的蓬勃发展,为生理兼容的纳米/微器件带来了很多关注,国际研究界正在寻找微尺度下驱动和运动的解决方案。本文描述了精子驱动的微型生物机器人在生物医学领域如药物递送或单细胞操作方面的潜力。在此,描述了精子驱动的微型生物机器人的一种特定潜力,它可能会对辅助生殖技术的发展产生影响。

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