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输尿管镜治疗嵌顿结石后输尿管狭窄的形成:一项前瞻性研究。

Ureteral stricture formation after ureteroscope treatment of impacted calculi: a prospective study.

作者信息

Fam Xeng Inn, Singam Praveen, Ho Christopher Chee Kong, Sridharan Radhika, Hod Rozita, Bahadzor Badrulhisham, Goh Eng Hong, Tan Guan Hee, Zainuddin Zulkifli

机构信息

Department of Surgery, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.

Department of Radiology, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.

出版信息

Korean J Urol. 2015 Jan;56(1):63-7. doi: 10.4111/kju.2015.56.1.63. Epub 2015 Jan 6.

Abstract

PURPOSE

Urinary calculi is a familiar disease. A well-known complication of endourological treatment for impacted ureteral stones is the formation of ureteral strictures, which has been reported to occur in 14.2% to 24% of cases.

MATERIALS AND METHODS

This was a prospective study. Ureterotripsy treatment was used on patients with impacted ureteral stones. Then, after 3 months and 6 months, the condition of these patients was assessed by means of a kidney-ureter-bladder (KUB) ultrasound. If the KUB ultrasound indicated moderate to serious hydronephrosis, the patient was further assessed by means of a computed tomography intravenous urogram or retrograde pyelogram to confirm the occurrence of ureteral strictures.

RESULTS

Of the 77 patients who participated in the study, 5 developed ureteral strictures. Thus, the stricture rate was 7.8%. An analysis of the intraoperative risk factors including perforation of the ureter, damage to the mucous membrane, and residual stone impacted within the ureter mucosa revealed that none of these factors contributed significantly to the formation of the ureteric strictures. The stone-related risk factors that were taken into consideration were stone size, stone impaction site, and duration of impaction. These stone factors also did not contribute significantly to the formation of the ureteral strictures.

CONCLUSIONS

This prospective study failed to identify any predictable factors for ureteral stricture formation. It is proposed that all patients undergo a simple postoperative KUB ultrasound screening 3 months after undergoing endoscopic treatment for impacted ureteral stones.

摘要

目的

尿路结石是一种常见疾病。输尿管结石嵌顿的腔内泌尿外科治疗的一种众所周知的并发症是输尿管狭窄的形成,据报道其发生率在14.2%至24%的病例中出现。

材料与方法

这是一项前瞻性研究。对输尿管结石嵌顿患者采用输尿管碎石术治疗。然后,在3个月和6个月后,通过肾脏-输尿管-膀胱(KUB)超声对这些患者的情况进行评估。如果KUB超声显示中度至重度肾积水,则通过计算机断层扫描静脉肾盂造影或逆行肾盂造影对患者进行进一步评估,以确认输尿管狭窄的发生。

结果

参与研究的77例患者中,有5例发生输尿管狭窄。因此,狭窄率为7.8%。对包括输尿管穿孔、黏膜损伤和输尿管黏膜内残留结石嵌顿在内的术中危险因素进行分析发现,这些因素均未对输尿管狭窄的形成有显著影响。所考虑的与结石相关的危险因素包括结石大小、结石嵌顿部位和嵌顿持续时间。这些结石因素也未对输尿管狭窄的形成有显著影响。

结论

这项前瞻性研究未能确定输尿管狭窄形成的任何可预测因素。建议所有患者在接受输尿管结石嵌顿的内镜治疗3个月后进行简单的术后KUB超声筛查。

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