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钬激光治疗输尿管结石:300例手术经验

Holmium: YAG lasertripsy for ureteric calculi: an experience of 300 procedures.

作者信息

Devarajan R, Ashraf M, Beck R O, Lemberger R J, Taylor M C

机构信息

Department of Urology, King's Mill Hospital, Sutton-in-Ashfield, UK.

出版信息

Br J Urol. 1998 Sep;82(3):342-7. doi: 10.1046/j.1464-410x.1998.00754.x.

Abstract

OBJECTIVE

To assess the success of holmium:YAG lasertripsy in the management of ureteric calculi and to audit the complications of the procedure, with special reference to strictures in the ureter.

PATIENTS AND METHODS

A total of 300 ureteroscopic laser procedures were carried out on 265 patients (204 male and 61 female, median age 51 years, range 2-95) with ureteric calculi. At ureteroscopy, the calculi were present in the upper ureter in 44%, mid-ureter in 37% and lower ureter in 19% of patients; most calculi were > 5 mm. A 7.5 F Wolf semi-rigid ureteroscope was used and the holmium:YAG laser energy delivered using the Sharplan ML210 device at 0.8-1.0 J/pulse. The patients were followed up at approximately 6 weeks with limited intravenous urography or ultrasonography to assess clearance and the incidence of strictures.

RESULTS

Stones were completely cleared in 90% of the patients, with the best results in the lower and mid-ureter (97% and 96%, respectively) followed by the upper ureter (89%). Alternative procedures were required in only 17 (7%) patients; extracorporeal shock-wave lithotripsy in 13, percutaneous nephrolithotomy in two and open pyelolithotomy in two patients. Complications with ureteric perforation in 11 patients, including laparotomy for peritonitis in one, serious sepsis in two and strictures in 10 patients. Strictures were more common in association with impacted calculi in the upper ureter early in the series.

CONCLUSIONS

Holmium:YAG lasertripsy is a highly effective treatment for ureteric calculi, with strictures related to the treatment of difficult upper ureteric calculi.

摘要

目的

评估钬激光碎石术治疗输尿管结石的成功率,并审查该手术的并发症,特别关注输尿管狭窄。

患者与方法

对265例(男性204例,女性61例,中位年龄51岁,范围2 - 95岁)输尿管结石患者共进行了300次输尿管镜激光手术。输尿管镜检查时,结石位于上段输尿管的患者占44%,中段输尿管的占37%,下段输尿管的占19%;大多数结石>5mm。使用7.5F Wolf半硬性输尿管镜,通过Sharplan ML210设备以0.8 - 1.0J/脉冲的能量发射钬激光。患者在大约6周时接受有限的静脉肾盂造影或超声检查随访,以评估结石清除情况和狭窄发生率。

结果

90%的患者结石完全清除,下段和中段输尿管的清除效果最佳(分别为97%和96%),其次是上段输尿管(89%)。仅17例(7%)患者需要进行其他手术;13例进行体外冲击波碎石术,2例进行经皮肾镜取石术,2例进行开放性肾盂切开取石术。11例患者发生输尿管穿孔并发症,其中1例因腹膜炎行剖腹手术,2例发生严重脓毒症,10例出现狭窄。在该系列研究早期,狭窄在上段输尿管嵌顿结石患者中更为常见。

结论

钬激光碎石术是治疗输尿管结石的高效方法,但存在与治疗上段输尿管复杂结石相关的狭窄问题。

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