Antshel Kevin M, Zhang-James Yanli, Wagner Kayla E, Ledesma Ana, Faraone Stephen V
a Department of Psychology , Syracuse University , Syracuse , NY , USA.
b Department of Psychiatry & Behavioral Sciences , SUNY-Upstate Medical University , Syracuse , NY , USA.
Expert Rev Neurother. 2016;16(3):279-93. doi: 10.1586/14737175.2016.1146591. Epub 2016 Feb 15.
Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) commonly co-occur. With the DSM-5, clinicians are permitted to make an ASD diagnosis in the context of ADHD. In earlier versions of the DSM, this was not acceptable. Both ASD and ADHD are reported to have had substantial increases in prevalence within the past 10 years. As a function of both the increased prevalence of both disorders as well as the ability to make an ASD diagnosis in ADHD, there has been a significant amount of research focusing on the comorbidity between ADHD and ASD in the past few years. Here, we provide an update on the biological, cognitive and behavioral overlap/distinctiveness between the two neurodevelopmental disorders with a focus on data published in the last four years. Treatment strategies for the comorbid condition as well as future areas of research and clinical need are discussed.
注意缺陷多动障碍(ADHD)和自闭症谱系障碍(ASD)常常共同出现。在《精神疾病诊断与统计手册》第五版(DSM - 5)中,临床医生被允许在ADHD的背景下做出ASD诊断。在DSM的早期版本中,这是不被接受的。据报道,在过去10年里,ASD和ADHD的患病率都大幅上升。由于这两种疾病患病率的增加以及在ADHD中做出ASD诊断的能力,在过去几年里,有大量研究聚焦于ADHD和ASD之间的共病情况。在此,我们提供这两种神经发育障碍在生物学、认知和行为方面的重叠/差异的最新情况,重点关注过去四年发表的数据。还讨论了共病情况的治疗策略以及未来的研究领域和临床需求。