2009年8月至2013年3月印度喜马偕尔邦甲型H1N1流感大流行和季节性流感的临床流行病学概况
Clinico-Epidemiological Profile, Pandemic Influenza A H1N1/2009 and Seasonal Influenza, August 2009-March 2013, Himachal Pradesh, India.
作者信息
Mehta Vinod Kumar, Sharma Pooja, Guleria Ramesh Chand, Ganju Sunite A, Singh Digvijay, Kanga Anil
机构信息
Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
出版信息
Indian J Community Med. 2016 Jan-Mar;41(1):69-71. doi: 10.4103/0970-0218.170995.
BACKGROUND
Novel influenza A (H1N1) virus emerged in April, 2009, spread rapidly to become pandemic by June, 2009.
OBJECTIVE
To study the clinco-epidemiological profile of pH1N1and seasonal influenza (SI) from 2009 to 2013.
MATERIALS AND METHODS
Retrospective, hospital-based study was done by reviewing medical records for collecting demographic and clinical profile of the study samples.
RESULT
Out of 969 samples, positivity and case fatality for pH1N1 and SI was 9.39 and 20.87% vs 11.76 and 7.89%, respectively. Among pH1N1and SI, sex distribution, mean age, and age group involved were 54.95% females, 37.10 years, and 20-29 years (23.08%) vs 43.86% females, 40.32 years, and 20-29 years (22.81%), respectively. Mortality shift was observed from younger to older and healthier, 75% to comorbid, 100% from 2009-2010 to 2012-13 for pH1N1.
CONCLUSION
We observed seasonal variation, cocirculation, similar clinical features, decreased virulence, and community spread with respect to pH1N1 and SI from 2009-2013.
背景
新型甲型H1N1流感病毒于2009年4月出现，到2009年6月迅速传播成为大流行病。
目的
研究2009年至2013年pH1N1流感和季节性流感（SI）的临床流行病学特征。
材料与方法
通过回顾病历进行基于医院的回顾性研究，以收集研究样本的人口统计学和临床特征。
结果
在969个样本中，pH1N1流感和季节性流感的阳性率和病死率分别为9.39%和20.87%，以及11.76%和7.89%。在pH1N1流感和季节性流感中，女性比例分别为54.95%和43.86%，平均年龄分别为37.10岁和40.32岁，涉及的年龄组分别为20 - 29岁（23.08%）和20 - 29岁（22.81%）。观察到pH1N1流感的死亡趋势从较年轻、健康人群转向年龄较大、有合并症人群，从2009 - 2010年到2012 - 2013年，有合并症人群的死亡率从75%升至100%。
结论
我们观察到2009 - 2013年期间，pH1N1流感和季节性流感存在季节性变化、共同流行、相似的临床特征、毒力下降以及社区传播的情况。
Zotero 插件