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预处理双氯芬酸钠对根管治疗后疼痛的影响:一项随机对照试验。

Effect of pretreatment diclofenac sodium on postendodontic pain: A randomised controlled trial.

作者信息

Metri Malasiddappa, Hegde Swaroop, Bhandi Shilpa

机构信息

Department of Conservative Dentistry and Endodontics, PMNM Dental College and Hospital, Bagalkot, Karnataka, India.

Department of Conservative Dentistry and Endodontics, M S Ramaiah Dental College and Hospital, Bengaluru, Karnataka, India.

出版信息

J Conserv Dent. 2016 Jan-Feb;19(1):7-10. doi: 10.4103/0972-0707.173183.

Abstract

INTRODUCTION

Effective management of endodontic pain represents a continuing challenge. Many of the dental professionals are facing significant problems associated with postendodontic pain. Hence, the postendodontic pain has to be prevented at its primary stage without waiting for its occurrence. This trial was carried out to evaluate the use of a preoperative, single oral dose of diclofenac sodium for the prevention and control of postendodontic pain.

MATERIALS AND METHODS

Fifty patients were randomly assigned to two groups, placebo and diclofenac sodium (100 mg). The medications were administered 30 min before the start of standard endodontic treatment. Postoperative pain was assessed after 6, 12, and 24 h by using a visual analog scale.

RESULTS

Postendodontic pain showed a statistically significant difference between both groups at 6 and 12 h (P < 0.05) and there was no significant difference at 24 h.

CONCLUSION

Postendodontic pain was substantially reduced by preoperative administration of single oral dose of diclofenac sodium. It is thus possible to conclude that these favorable results might help to prevent postendodontic pain, especially in patients with a low pain threshold.

摘要

引言

有效管理牙髓疼痛仍然是一项持续的挑战。许多牙科专业人员面临与根管治疗后疼痛相关的重大问题。因此,必须在根管治疗后疼痛的初始阶段就进行预防,而不是等待其出现。本试验旨在评估术前单次口服双氯芬酸钠对预防和控制根管治疗后疼痛的作用。

材料与方法

50名患者被随机分为两组,即安慰剂组和双氯芬酸钠组(100毫克)。在标准根管治疗开始前30分钟给药。术后6、12和24小时使用视觉模拟量表评估疼痛情况。

结果

根管治疗后疼痛在6小时和12小时时两组间有统计学显著差异(P < 0.05),24小时时无显著差异。

结论

术前单次口服双氯芬酸钠可显著减轻根管治疗后疼痛。因此可以得出结论,这些良好结果可能有助于预防根管治疗后疼痛,尤其是对疼痛阈值较低的患者。

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Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial.
J Endod. 2010 Jun;36(6):978-81. doi: 10.1016/j.joen.2010.03.015. Epub 2010 Apr 24.
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