Dheeraj Munish, Johar Suksham, Mahajan Priya, Jandial Tania, Chauhan Shikha, Gupta Kamakshi
Senior Resident, Department of Dentistry, Andaman and Nicobar Islands Institute of Meical Sciences, Port Blair, Andaman and Nicobar Islands, India.
Conservative Dentistry and Endodontics, Desh Bhagat Dental College and General Hospital, Mandi Govindgarh, Punjab, India.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1283-S1286. doi: 10.4103/jpbs.jpbs_119_23. Epub 2023 Jul 11.
This study aimed to compare the efficacy of two modes of delivery of diclofenac for the management of post-endodontic pain.
This study comprised 30 patients reporting to the department with pain in their teeth. Pain was assessed using the visual analog scale (VAS): group A (control group), group B (oral diclofenac), and group C (transdermal patch). A VAS was given to the patients in each group, and the severity of any pain was self-assessed by patients after 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs following the completion of treatment.
A comparison between group oral and diclofenac transdermal patch was carried out. The pain frequency was measured at 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs postoperatively with values of 0.744, 0.035, 0.570, 0.060, and 0.508 and was statistically insignificant.
Preoperative analgesics play an important role in reducing post-endodontic pain. Transdermal patches containing diclofenac show a promising analgesic modality in managing endodontic pain.
本研究旨在比较双氯芬酸两种给药方式在治疗根管治疗后疼痛方面的疗效。
本研究纳入30例因牙齿疼痛前来科室就诊的患者。使用视觉模拟量表(VAS)评估疼痛程度:A组(对照组)、B组(口服双氯芬酸)和C组(透皮贴剂)。为每组患者提供VAS,患者在治疗结束后4小时、8小时、12小时、24小时和48小时自行评估任何疼痛的严重程度。
对口服双氯芬酸组和透皮贴剂组进行了比较。术后4小时、8小时、12小时、24小时和48小时测量疼痛频率,数值分别为0.744、0.035、0.570、0.060和0.508,差异无统计学意义。
术前镇痛药在减轻根管治疗后疼痛方面发挥着重要作用。含双氯芬酸的透皮贴剂在治疗根管治疗疼痛方面显示出有前景的镇痛方式。