Suppr超能文献

双氯芬酸两种给药方式治疗根管治疗后疼痛疗效的比较评价:一项随机对照临床试验

Comparative Evaluation of the Efficacy of Two Modes of Delivery of Diclofenac for the Management of Post-Endodontic Pain: A Randomized Controlled Clinical Trial.

作者信息

Dheeraj Munish, Johar Suksham, Mahajan Priya, Jandial Tania, Chauhan Shikha, Gupta Kamakshi

机构信息

Senior Resident, Department of Dentistry, Andaman and Nicobar Islands Institute of Meical Sciences, Port Blair, Andaman and Nicobar Islands, India.

Conservative Dentistry and Endodontics, Desh Bhagat Dental College and General Hospital, Mandi Govindgarh, Punjab, India.

出版信息

J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1283-S1286. doi: 10.4103/jpbs.jpbs_119_23. Epub 2023 Jul 11.

Abstract

BACKGROUND

This study aimed to compare the efficacy of two modes of delivery of diclofenac for the management of post-endodontic pain.

MATERIALS AND METHODS

This study comprised 30 patients reporting to the department with pain in their teeth. Pain was assessed using the visual analog scale (VAS): group A (control group), group B (oral diclofenac), and group C (transdermal patch). A VAS was given to the patients in each group, and the severity of any pain was self-assessed by patients after 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs following the completion of treatment.

RESULTS

A comparison between group oral and diclofenac transdermal patch was carried out. The pain frequency was measured at 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs postoperatively with values of 0.744, 0.035, 0.570, 0.060, and 0.508 and was statistically insignificant.

CONCLUSION

Preoperative analgesics play an important role in reducing post-endodontic pain. Transdermal patches containing diclofenac show a promising analgesic modality in managing endodontic pain.

摘要

背景

本研究旨在比较双氯芬酸两种给药方式在治疗根管治疗后疼痛方面的疗效。

材料与方法

本研究纳入30例因牙齿疼痛前来科室就诊的患者。使用视觉模拟量表(VAS)评估疼痛程度:A组(对照组)、B组(口服双氯芬酸)和C组(透皮贴剂)。为每组患者提供VAS,患者在治疗结束后4小时、8小时、12小时、24小时和48小时自行评估任何疼痛的严重程度。

结果

对口服双氯芬酸组和透皮贴剂组进行了比较。术后4小时、8小时、12小时、24小时和48小时测量疼痛频率,数值分别为0.744、0.035、0.570、0.060和0.508,差异无统计学意义。

结论

术前镇痛药在减轻根管治疗后疼痛方面发挥着重要作用。含双氯芬酸的透皮贴剂在治疗根管治疗疼痛方面显示出有前景的镇痛方式。

相似文献

4
The efficacy of transdermal and oral diclofenac for post-endodontic pain control: A randomised controlled trial.
Indian J Dent Res. 2020 Jan-Feb;31(1):53-56. doi: 10.4103/ijdr.IJDR_167_17.

引用本文的文献

1
A Framework for the Modulation and Alleviation of Pain Sensations: A Narrative Review.
Cureus. 2025 May 5;17(5):e83508. doi: 10.7759/cureus.83508. eCollection 2025 May.

本文引用的文献

1
Postendodontic pain: a practical approach to diagnosis and management.
Quintessence Int. 2021 Apr 8;52(5):384-392. doi: 10.3290/j.qi.b1044039.
2
Effect of pretreatment diclofenac sodium on postendodontic pain: A randomised controlled trial.
J Conserv Dent. 2016 Jan-Feb;19(1):7-10. doi: 10.4103/0972-0707.173183.
3
Single dose oral diclofenac for acute postoperative pain in adults.
Cochrane Database Syst Rev. 2015 Jul 7;2015(7):CD004768. doi: 10.1002/14651858.CD004768.pub3.
4
Gender differences in analgesia for endodontic pain.
J Endod. 2008 May;34(5):552-6. doi: 10.1016/j.joen.2008.01.021. Epub 2008 Mar 24.
5
Comparison of methylprednisolone and ketoprofen after multiple third molar extraction: a randomized controlled study.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jan;103(1):e7-9. doi: 10.1016/j.tripleo.2006.07.005. Epub 2006 Oct 6.
8
Analgesic safety and efficacy of diclofenac sodium softgels on postoperative third molar extraction pain.
J Oral Maxillofac Surg. 2004 Jul;62(7):806-15. doi: 10.1016/j.joms.2003.12.019.
10
Topical NSAIDs for acute pain: a meta-analysis.
BMC Fam Pract. 2004 May 17;5:10. doi: 10.1186/1471-2296-5-10.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验