Scipion：一个用于三维电子显微镜集成、可重复性和验证的软件框架。
Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy.
作者信息
de la Rosa-Trevín J M, Quintana A, Del Cano L, Zaldívar A, Foche I, Gutiérrez J, Gómez-Blanco J, Burguet-Castell J, Cuenca-Alba J, Abrishami V, Vargas J, Otón J, Sharov G, Vilas J L, Navas J, Conesa P, Kazemi M, Marabini R, Sorzano C O S, Carazo J M
机构信息
Biocomputing Unit, National Center for Biotechnology (CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain; Escuela Politécnica Superior, Universidad Autónoma de Madrid, Campus Universidad Autónoma, 28049 Cantoblanco, Madrid, Spain.
Neuroscience, Physiology and Pharmacology Dept., Univ. College London, Gower Street, London WC1E 6BT, United Kingdom.
出版信息
J Struct Biol. 2016 Jul;195(1):93-9. doi: 10.1016/j.jsb.2016.04.010. Epub 2016 Apr 20.
In the past few years, 3D electron microscopy (3DEM) has undergone a revolution in instrumentation and methodology. One of the central players in this wide-reaching change is the continuous development of image processing software. Here we present Scipion, a software framework for integrating several 3DEM software packages through a workflow-based approach. Scipion allows the execution of reusable, standardized, traceable and reproducible image-processing protocols. These protocols incorporate tools from different programs while providing full interoperability among them. Scipion is an open-source project that can be downloaded from http://scipion.cnb.csic.es.
在过去几年中，三维电子显微镜（3DEM）在仪器设备和方法学方面经历了一场变革。这场影响广泛的变革的核心推动因素之一是图像处理软件的持续发展。在此，我们介绍Scipion，这是一个通过基于工作流程的方法来集成多个3DEM软件包的软件框架。Scipion允许执行可重复使用、标准化、可追溯且可重现的图像处理协议。这些协议整合了来自不同程序的工具，同时在它们之间提供了完全的互操作性。Scipion是一个开源项目，可从http://scipion.cnb.csic.es下载。
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