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小儿急性糖尿病酮症酸中毒的神经影像学表现

Neuroimaging findings in acute pediatric diabetic ketoacidosis.

作者信息

Barrot Alaysia, Huisman Thierry Agm, Poretti Andrea

机构信息

Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, USA.

Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, USA

出版信息

Neuroradiol J. 2016 Oct;29(5):317-22. doi: 10.1177/1971400916665389. Epub 2016 Aug 16.

Abstract

Diabetic ketoacidosis (DKA) is a state of severe insulin deficiency and a serious complication in children with diabetes mellitus type 1. In a small number of children, DKA is complicated by injury of the central nervous system. These children have a significant mortality and high long-term neurological morbidity. Cerebral edema is the most common neuroimaging finding in children with DKA and may cause brain herniation. Ischemic or hemorrhagic stroke during the acute DKA episode is less common and accounts for approximately 10% of intracerebral complications of DKA. Here we present the neuroimaging findings of two children with DKA and brain injury. Familiarity with the spectrum of neuroimaging findings seen in pediatric DKA is important to allow early detection as well as initiation of therapy and, hence, prevent complications of the central nervous system.

摘要

糖尿病酮症酸中毒(DKA)是一种严重胰岛素缺乏的状态,是1型糖尿病患儿的一种严重并发症。在少数儿童中,DKA会并发中枢神经系统损伤。这些儿童有较高的死亡率和长期神经疾病发病率。脑水肿是DKA患儿最常见的神经影像学表现,可能导致脑疝。急性DKA发作期间的缺血性或出血性中风较少见,约占DKA颅内并发症的10%。在此,我们展示了两名患有DKA和脑损伤儿童的神经影像学表现。熟悉小儿DKA的神经影像学表现范围对于早期发现、启动治疗以及预防中枢神经系统并发症很重要。

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