Division of Health Economics, Policy and Management, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Queen Elizabeth Hospital, Hong Kong.
Diabet Med. 2017 Jul;34(7):902-908. doi: 10.1111/dme.13284. Epub 2016 Nov 29.
To estimate recent secular changes in the incidence and prevalence of diabetes and pre-diabetes among Hong Kong Chinese adults, and thus show possible future trends for developing mainland China.
Based on a complete census of the public sector health records of 6.4 million people from 2006 to 2014, diabetes cases were ascertained using different methods including the World Health Organization (WHO) 2011 guidelines (HbA , fasting plasma glucose and glucose tolerance test), American Diabetes Association (ADA) 2015 guidelines (plus random plasma glucose), and additionally recorded diagnosis codes and medication dispensation. Pre-diabetes was defined using ADA 2015 guidelines.
We identified 697 201 people with diabetes (54.2% were incident cases); and 1 229 731 people with diabetes or pre-diabetes. In 2014, the overall incidence of diabetes was 9.46 per 1000 person-years [95% confidence interval (CI): 9.38 to 9.54], and overall prevalence was 10.29% (95% CI: 10.27% to 10.32%). Incidence of diabetes decreased significantly from 2007 to 2014 (quadratic trend, P < 0.001). From 2006 to 2014, the prevalence of diabetes increased significantly in both sexes and across all age groups (quadratic trend, P < 0.001). The overall incidence of pre-diabetes in 2014 was 18.88 per 1000 person-years (95% CI: 18.76 to 18.99), and the overall prevalence of pre-diabetes was 8.90% (95% CI: 8.87% to 8.92%).
Similar to other developed western and Asian populations, diabetes (and pre-diabetes) incidence in Hong Kong Chinese appeared to have stabilized and there have been small declines during the period of observation. Ageing and survivorship will likely drive a continued increase in the prevalence of diabetes and pre-diabetes, albeit with a decelerating growth rate if past trends persist.
估计香港华人成年人中糖尿病和糖尿病前期的发病率和患病率的近期变化,从而为中国大陆的未来趋势提供参考。
基于 2006 年至 2014 年公共部门 640 万人的完整人口普查数据,使用不同的方法确定糖尿病病例,包括世界卫生组织(WHO)2011 年指南(HbA1c、空腹血浆葡萄糖和葡萄糖耐量试验)、美国糖尿病协会(ADA)2015 年指南(加上随机血浆葡萄糖),以及另外记录的诊断代码和药物配给。使用 ADA 2015 年指南定义糖尿病前期。
我们共确定了 697201 例糖尿病患者(54.2%为新发病例);1229731 例糖尿病或糖尿病前期患者。2014 年,糖尿病总发病率为 9.46/1000 人年[95%置信区间(CI):9.38 至 9.54],总患病率为 10.29%(95%CI:10.27%至 10.32%)。糖尿病的发病率从 2007 年至 2014 年显著下降(二次趋势,P<0.001)。从 2006 年至 2014 年,两性和各年龄段的糖尿病患病率均显著增加(二次趋势,P<0.001)。2014 年糖尿病前期的总发病率为 18.88/1000 人年(95%CI:18.76 至 18.99),糖尿病前期的总患病率为 8.90%(95%CI:8.87%至 8.92%)。
与其他发达的西方和亚洲人群一样,香港华人的糖尿病(和糖尿病前期)发病率似乎已经稳定,在观察期间略有下降。随着人口老龄化和存活率的增加,糖尿病和糖尿病前期的患病率可能会持续上升,但如果过去的趋势持续下去,增长速度将会减缓。