抗菌药物管理：微生物实验室如何扭转局面。
Antimicrobial Stewardship: How the Microbiology Laboratory Can Right the Ship.
作者信息
Morency-Potvin Philippe, Schwartz David N, Weinstein Robert A
机构信息
Division of Infectious Diseases, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA
Rush Medical College, Chicago, Illinois, USA.
出版信息
Clin Microbiol Rev. 2016 Dec 14;30(1):381-407. doi: 10.1128/CMR.00066-16. Print 2017 Jan.
Antimicrobial stewardship is a bundle of integrated interventions employed to optimize the use of antimicrobials in health care settings. While infectious-disease-trained physicians, with clinical pharmacists, are considered the main leaders of antimicrobial stewardship programs, clinical microbiologists can play a key role in these programs. This review is intended to provide a comprehensive discussion of the different components of antimicrobial stewardship in which microbiology laboratories and clinical microbiologists can make significant contributions, including cumulative antimicrobial susceptibility reports, enhanced culture and susceptibility reports, guidance in the preanalytic phase, rapid diagnostic test availability, provider education, and alert and surveillance systems. In reviewing this material, we emphasize how the rapid, and especially the recent, evolution of clinical microbiology has reinforced the importance of clinical microbiologists' collaboration with antimicrobial stewardship programs.
抗菌药物管理是一系列综合干预措施，用于优化医疗环境中抗菌药物的使用。虽然受过传染病培训的医生与临床药师被视为抗菌药物管理计划的主要领导者，但临床微生物学家在这些计划中也可以发挥关键作用。本综述旨在全面讨论抗菌药物管理的不同组成部分，其中微生物学实验室和临床微生物学家可做出重大贡献，包括累积抗菌药物敏感性报告、强化培养和敏感性报告、分析前阶段的指导、快速诊断测试的可用性、提供者教育以及警报和监测系统。在回顾这些材料时，我们强调临床微生物学的快速发展，尤其是近期的发展，如何强化了临床微生物学家与抗菌药物管理计划合作的重要性。
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