a Department of Chemistry , University of Swabi , Khyber Pakhtunkhwa , Pakistan.
b Department of Diet and Nutritional Sciences , Imperial College of Business Studies , Lahore , Pakistan.
Crit Rev Food Sci Nutr. 2018 Jun 13;58(9):1428-1447. doi: 10.1080/10408398.2016.1263597. Epub 2017 Jul 21.
Owing to their antimicrobial, antioxidant, and anti-inflammatory activity, grapes (Vitis vinifera L.) are the archetypal paradigms of fruits used not only for nutritional purposes, but also for exclusive therapeutics. Grapes are a prominent and promising source of phytochemicals, especially resveratrol, a phytoalexin antioxidant found in red grapes which has both chemopreventive and therapeutic effects against various ailments. Resveratrol's role in reducing different human cancers, including breast, cervical, uterine, blood, kidney, liver, eye, bladder, thyroid, esophageal, prostate, brain, lung, skin, gastric, colon, head and neck, bone, ovarian, and cervical, has been reviewed. This review covers the literature that deals with the anti-cancer mechanism of resveratrol with special reference to antioxidant potential. Furthermore, this article summarizes the literature pertaining to resveratrol as an anti-cancer agent.
由于葡萄(Vitis vinifera L.)具有抗菌、抗氧化和抗炎活性,因此成为不仅用于营养目的,而且还用于独特治疗的水果的典型范例。葡萄是植物化学物质的突出且有前途的来源,特别是白藜芦醇,它是一种在红葡萄中发现的植物抗毒素抗氧化剂,对各种疾病具有化学预防和治疗作用。白藜芦醇在降低不同人类癌症(包括乳腺癌、宫颈癌、子宫癌、血液癌、肾癌、肝癌、眼癌、膀胱癌、甲状腺癌、食道癌、前列腺癌、脑癌、肺癌、皮肤癌、胃癌、结肠癌、头颈部癌、骨癌、卵巢癌和宫颈癌)中的作用已被综述。这篇综述涵盖了有关白藜芦醇抗癌机制的文献,特别提到了抗氧化潜力。此外,本文还总结了有关白藜芦醇作为抗癌剂的文献。