Onuoha Onyi C
Department of Anesthesiology and Critical Care, Perelman School of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Dulles 6, Philadelphia, PA 19104, USA.
Anesthesiol Clin. 2017 Mar;35(1):1-14. doi: 10.1016/j.anclin.2016.09.003. Epub 2016 Dec 12.
Despite the traditional practice to maintain labor analgesia with a combination of continuous epidural infusion and patient-controlled epidural analgesia using an automated epidural pump; compelling data now shows that bolus injection through the epidural catheter may result in better distribution of anesthetic solution in the epidural space. The programmed intermittent epidural bolus technique is proposed as a better maintenance mode and may represent a more effective mode of maintaining epidural analgesia for labor, especially prolonged labor. Additional prospective and adequately powered studies are needed to confirm findings and determine the optimal combination of volume, rate, time, and drug concentration.
尽管传统做法是通过持续硬膜外输注和使用自动硬膜外泵的患者自控硬膜外镇痛相结合来维持分娩镇痛,但现在有令人信服的数据表明,通过硬膜外导管进行推注可能会使麻醉溶液在硬膜外间隙中分布得更好。程序化间歇性硬膜外推注技术被提议作为一种更好的维持模式,可能代表一种更有效的分娩硬膜外镇痛维持模式,尤其是对于产程延长的情况。需要更多前瞻性且有足够样本量的研究来证实这些发现,并确定剂量、速率、时间和药物浓度的最佳组合。