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喀麦隆孕妇感染的血清阳性率。

Seroprevalence of infection among pregnant women in Cameroon.

作者信息

Njunda Anna L, Assob Jules C N, Nsagha Dickson S, Kamga Henri L, Nde Peter F, Yugah Vuchas C

机构信息

Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Buea.

Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea.

出版信息

J Public Health Afr. 2011 Sep 5;2(2):e24. doi: 10.4081/jphia.2011.e24.

Abstract

Toxoplasmosis is caused by an intracellular protozoan, , which has a wide geographical distribution. The congenital form results in a gestational form that can present a temporary parasiteamia that will infect the fetus. For this reason early diagnosis in pregnancy is highly desirable, allowing prompt intervention in cases of infection. The aim of this study was to determine the seroprevalence of antibodies among pregnant women attending the Douala General Hospital. The study was carried out between March and July 2009, whereby 110 pregnant women were tested for IgG and IgM antibodies and information about eating habits and hygienic conditions was collected using a questionnaire. These women's ages ranged from 20-44 years old with an average of 29.9 years; the overall IgG and IgM seroprevalence was 70% and 2.73 % respectively. Seroprevalence was significantly high amongst women who ate raw vegetables (76.39%, P<0.05) and there was a significant trend towards a higher seroprevalence in women who did not have a good source of water (75.58%, P<0.05). This research showed that consumption of raw vegetables and poor quality drinking water are two risk factors associated with infection amongst pregnant women attending the Douala General Hospital in Cameroon.

摘要

弓形虫病由一种细胞内原生动物引起,其地理分布广泛。先天性弓形虫病会导致孕期感染,出现短暂的寄生虫血症,进而感染胎儿。因此,孕期尽早诊断非常必要,以便在感染病例中及时进行干预。本研究的目的是确定在杜阿拉综合医院就诊的孕妇中弓形虫抗体的血清流行率。该研究于2009年3月至7月进行,对110名孕妇进行了IgG和IgM抗体检测,并通过问卷调查收集了她们的饮食习惯和卫生状况信息。这些女性年龄在20至44岁之间,平均年龄为29.9岁;总体IgG和IgM血清流行率分别为70%和2.73%。食用生蔬菜的女性血清流行率显著较高(76.39%,P<0.05),水源不佳的女性血清流行率有显著升高趋势(75.58%,P<0.05)。这项研究表明,食用生蔬菜和饮用劣质水是喀麦隆杜阿拉综合医院就诊孕妇感染弓形虫的两个风险因素。

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