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肺癌患者的焦虑和抑郁强度与生活质量的关系。

Intensity of Anxiety and Depression in Patients with Lung Cancer in Relation to Quality of Life.

机构信息

Lower Silesian Oncology Center, Home Hospice, 12 Hirszfeld Square, 53-413, Wroclaw, Poland.

Division of Surgical Procedures, Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 5 Bartla Street, 51-618, Wroclaw, Poland.

出版信息

Adv Exp Med Biol. 2018;1023:29-36. doi: 10.1007/5584_2017_50.

Abstract

Psychological factors, such as the anxiety and depression, which often occur in patients with lung cancer might negatively influence their quality of life. The aim of the study was to evaluate the effect of anxiety and depression in lung cancer patients on quality of life. The study included 180 lung patients of the mean age of 62.7 ± 9.7 years. The following scales were employed in the study: Quality of Life Questionnaire QLQ-C30 and LC13 scale, and Hospital Anxiety and Depression scale (HADS). The overall score of quality of life measured by QLQ-C30 was 47.1 ± 23.4 points on a hundred-point scale. Anxiety was diagnosed in 67 patients (37.2%) and depression in 75 patients (41.7%) by HADS. Quality of life was significantly worse in case of anxiety and depression (p < 0.05), which negatively influenced both functional and symptom intensity scales measured with QLQ-C30 and QLQ-LC13. We conclude that early identification of anxiety and depression may help in therapeutic decision-making and may be a useful predictive factor in lung cancer patients.

摘要

心理因素,如肺癌患者常出现的焦虑和抑郁,可能会对他们的生活质量产生负面影响。本研究旨在评估肺癌患者的焦虑和抑郁对生活质量的影响。该研究纳入了 180 名平均年龄为 62.7 ± 9.7 岁的肺癌患者。研究中使用了以下量表:生活质量问卷 QLQ-C30 和 LC13 量表以及医院焦虑和抑郁量表(HADS)。在 100 分制中,QLQ-C30 测量的整体生活质量评分得分为 47.1 ± 23.4 分。通过 HADS,有 67 名患者(37.2%)被诊断为焦虑,75 名患者(41.7%)被诊断为抑郁。焦虑和抑郁的患者生活质量明显更差(p < 0.05),这会对 QLQ-C30 和 QLQ-LC13 测量的功能和症状强度量表产生负面影响。我们的结论是,早期识别焦虑和抑郁可能有助于治疗决策,并可能成为肺癌患者的一个有用的预测因素。

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