糖基化金纳米粒子：合成与应用
Glyco-gold nanoparticles: synthesis and applications.
作者信息
Compostella Federica, Pitirollo Olimpia, Silvestri Alessandro, Polito Laura
机构信息
Department of Medical Biotechnology and Translational Medicine, University of Milan, Via Saldini 50, 20133 Milan, Italy.
Department of Chemistry, University of Milan, Via C. Golgi 19, 20133 Milan, Italy.
出版信息
Beilstein J Org Chem. 2017 May 24;13:1008-1021. doi: 10.3762/bjoc.13.100. eCollection 2017.
Glyco-gold nanoparticles combine in a single entity the peculiar properties of gold nanoparticles with the biological activity of carbohydrates. The result is an exciting nanosystem, able to mimic the natural multivalent presentation of saccharide moieties and to exploit the peculiar optical properties of the metallic core. In this review, we present recent advances on glyco-gold nanoparticle applications in different biological fields, highlighting the key parameters which inspire the glyco nanoparticle design.
糖基化金纳米颗粒将金纳米颗粒的独特性质与碳水化合物的生物活性结合于单一实体中。其结果是一个令人兴奋的纳米系统，它能够模拟糖类部分的天然多价呈现，并利用金属核的独特光学性质。在这篇综述中，我们介绍了糖基化金纳米颗粒在不同生物领域应用的最新进展，突出了启发糖基纳米颗粒设计的关键参数。
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