拓展组织工具包：从人类多能干细胞中获得结肠组织。
Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells.
机构信息
Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
出版信息
Cell Stem Cell. 2017 Jul 6;21(1):3-5. doi: 10.1016/j.stem.2017.06.001.
Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue.
类器官技术在疾病建模和再生医学方面具有巨大潜力。在本期《细胞—干细胞》杂志上，Múnera 等人（2017 年）建立了多能干细胞衍生的结肠类器官的生成方法，这些类器官在移植到小鼠体内后，在很大程度上类似于人类结肠，为研究人类结肠组织中的疾病发病机制开辟了途径。
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