Alaid Awad, von Eckardstein Kajetan, Smoll Nicolas Roydon, Solomiichuk Volodymyr, Rohde Veit, Martinez Ramon, Schatlo Bawarjan
Department of Neurosurgery, University Medicine Göttingen Georg-August-University of Göttingen, Göttingen, Germany.
School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.
Neurosurg Rev. 2018 Apr;41(2):489-496. doi: 10.1007/s10143-017-0877-1. Epub 2017 Jul 20.
Postoperative wound healing can pose a problem in patients undergoing instrumented surgery for pyogenic spondylodiscitis. Robotic guidance allows the minimally invasive placement of pedicle screws in the thoracolumbar spine. We assessed whether using this technique to perform minimally invasive surgery had an impact on wound healing in patients with pyogenic spondylodiscitis when compared to conventional open fluoroscopy-guided surgery. We reviewed charts of 206 consecutive patients who underwent instrumentation for pyogenic spondylodiscitis. The need for wound revision was the primary outcome measure. Patient variables and comorbidities as well as surgical technique (robotic versus fluoroscopy-guided) were analyzed. We also compared fluoroscopy times between the two groups. Multivariate regression analysis was performed to identify predictors of wound breakdown. A total of 206 patients underwent surgery for spondylodiscitis. Robotic surgical assistance was used for percutaneous instrumentation in 47.6% of cases (n = 98). Wound healing problems requiring revision occurred in 30 out of 206 patients (14.6%). Univariate analysis revealed a potential association of wound breakdown with (1) robotic technique, (2) age > 70 years, and (3) the presence of methicillin-resistant Staphylococcus aureus. After multivariate correction however, only robotic technique retained significance with an odds ratio of 0.39 (CI 95% 0.16-0.94; p = 0.035). Wound revision was required in eight out of 98 patients (8.1%) in the robot group and 22/108 (20%) in the conventional surgery group. Fluoroscopy times were significantly lower in the robot group with a mean of 123 ± 86 s in comparison with a mean of 157 ± 99 s in the conventional group (p = 0.014). While initially designed to improve the accuracy of pedicle screw placement, robot-assisted minimally invasive technique had a tangible effect on both radiation exposure and the rate of wound breakdown in patients with pyogenic spondylodiscitis in our large single-center study.
对于接受化脓性脊椎间盘炎手术治疗的患者,术后伤口愈合可能会成为一个问题。机器人引导技术可实现胸腰椎椎弓根螺钉的微创置入。我们评估了与传统的开放荧光透视引导手术相比,采用该技术进行微创手术对化脓性脊椎间盘炎患者伤口愈合是否有影响。我们回顾了206例连续接受化脓性脊椎间盘炎手术治疗患者的病历。伤口修复需求是主要的观察指标。分析了患者变量、合并症以及手术技术(机器人辅助与荧光透视引导)。我们还比较了两组的透视时间。进行多因素回归分析以确定伤口裂开的预测因素。共有206例患者接受了脊椎间盘炎手术。47.6%的病例(n = 98)使用机器人手术辅助进行经皮器械置入。206例患者中有30例(14.6%)出现需要修复的伤口愈合问题。单因素分析显示伤口裂开与以下因素可能有关:(1)机器人技术;(2)年龄>70岁;(3)耐甲氧西林金黄色葡萄球菌感染。然而,经过多因素校正后,只有机器人技术具有显著意义,比值比为0.39(95%CI 0.16 - 0.94;p = 0.035)。机器人组98例患者中有8例(8.1%)需要进行伤口修复,传统手术组108例中有22例(20%)。机器人组的透视时间显著更短,平均为123±86秒,而传统组平均为157±99秒(p = 0.014)。在我们这项大型单中心研究中,最初旨在提高椎弓根螺钉置入准确性的机器人辅助微创技术,对化脓性脊椎间盘炎患者的辐射暴露和伤口裂开率均产生了切实影响。