INSERM Ethics Committee, Paris, France.
National Centre for Biotechnology (CNB-CSIC), CSIC Ethics Committee and CIBERER-ISCIII, Madrid, Spain.
Transgenic Res. 2017 Oct;26(5):709-713. doi: 10.1007/s11248-017-0028-z. Epub 2017 Jul 20.
In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome editing (off-targets, mosaicisms, etc.), and to design risk matrices and scenarios for a responsible use of this promising technology. In addition, this European steering committee will contribute in promoting an open debate on societal aspects prior to a translation into national and international legislation.
在这份由来自 20 多个欧洲合作伙伴的代表参与的会议达成的共识文件中,我们建议成立一个专家组(欧洲指导委员会),评估基因组编辑(脱靶效应、嵌合体等)的潜在益处和弊端,并设计风险矩阵和方案,以负责任地使用这项有前途的技术。此外,该欧洲指导委员会将为在转化为国家和国际立法之前,就社会层面问题进行公开辩论做出贡献。