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西班牙成年人群体中风湿性疾病的患病率(EPISER 2016研究):目标与方法

Prevalence of rheumatic diseases in adult population in Spain (EPISER 2016 study): Aims and methodology.

作者信息

Seoane-Mato Daniel, Sánchez-Piedra Carlos, Silva-Fernández Lucía, Sivera Francisca, Blanco Francisco J, Pérez Ruiz Fernando, Juan-Mas Antonio, Pego-Reigosa José M, Narváez Javier, Quilis Martí Neus, Cortés Verdú Raúl, Antón-Pagés Fred, Quevedo Vila Víctor, Garrido Courel Laura, Del Amo Natividad Del Val, Paniagua Zudaire Inmaculada, Añez Sturchio Gustavo, Medina Varo Fermín, Ruiz Tudela María Del Mar, Romero Pérez Antonio, Ballina Javier, Brandy García Anahy, Fábregas Canales Dolores, Font Gayá Teresa, Bordoy Ferrer Carolina, González Álvarez Beatriz, Casas Hernández Laura, Álvarez Reyes Fátima, Delgado Sánchez Mónica, Martínez Dubois Cristina, Sánchez-Fernández Simón Ángel, Rojas Vargas Luisa Marena, García Morales Paula Virginia, Olivé Alejandro, Rubio Muñoz Paula, Larrosa Marta, Navarro Ricos Noemí, Graell Martín Eduard, Chamizo Eugenio, Chaves Chaparro Lara, Rojas Herrera Sara, Pons Dolset Jordi, Polo Ostariz Miguel Ángel, Ruiz-Alejos Garrido Susana, Macía Villa Cristina, Cruz Valenciano Ana, González Gómez María Luisa, Morcillo Valle Mercedes, Palma Sánchez Deseada, Moreno Martínez María José, Mayor González Marta, Atxotegi Sáenz de Buruaga Joana, Urionagüena Onaindia Irati, Blanco Cáceres Boris Anthony, Díaz-González Federico, Bustabad Sagrario

机构信息

Unidad de Investigación, Sociedad Española de Reumatología, Madrid, España.

Servicio de Reumatología, Complexo Hospitalario Universitario de Ferrol, Ferrol, A Coruña, España.

出版信息

Reumatol Clin (Engl Ed). 2019 Mar-Apr;15(2):90-96. doi: 10.1016/j.reuma.2017.06.009. Epub 2017 Jul 31.

Abstract

AIMS

To describe the methodology of the EPISER 2016 (study of the prevalence of rheumatic diseases in adult population in Spain), as well its strengths and limitations. The aim of this study is to estimate the prevalence of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), Sjögren's syndrome (SS), osteoarthritis (knee, hip, hands, and cervical and lumbar spine), fibromyalgia, gout and clinical osteoporotic fracture.

MATERIAL AND METHOD

Population-based, multicenter, cross-sectional study, with the participation of 45 municipalities in the 17 Spanish autonomous communities. The reference population will consist of adults aged 20 years and over residing in Spain. A computer-assisted telephone interview (CATI) system will be used for data collection. Diagnostic suspicions and diagnoses received by the participants will be studied by rheumatologists in the referral hospitals in the selected municipalities.

STATISTICAL ANALYSIS

the prevalence of the rheumatic diseases will be calculated using estimators and their 95% confidence intervals. Weights will be calculated in each of the sampling stages in accordance with the probability of selection. The distribution of the population in Spain will be obtained from the Spanish Statistics Institute.

CONCLUSIONS

Sociodemographic and lifestyle changes over the last 16 years justify EPISER 2016. This study will provide current data about the prevalences of RA, AS, PsA, SLE, SS, osteoarthritis, fibromyalgia, gout and clinical osteoporotic fracture. The results will allow comparisons with studies from other countries and EPISER 2000.

摘要

目的

描述2016年西班牙成人风湿性疾病患病率研究(EPISER 2016)的方法及其优势与局限性。本研究旨在估算类风湿关节炎(RA)、银屑病关节炎(PsA)、强直性脊柱炎(AS)、系统性红斑狼疮(SLE)、干燥综合征(SS)、骨关节炎(膝、髋、手以及颈椎和腰椎)、纤维肌痛、痛风和临床骨质疏松性骨折的患病率。

材料与方法

基于人群的多中心横断面研究,西班牙17个自治区的45个城市参与其中。参考人群将包括居住在西班牙的20岁及以上成年人。数据收集将使用计算机辅助电话访谈(CATI)系统。参与者收到的诊断怀疑和诊断结果将由选定城市转诊医院的风湿病学家进行研究。

统计分析

将使用估计量及其95%置信区间计算风湿性疾病的患病率。将根据选择概率在每个抽样阶段计算权重。西班牙人口分布数据将从西班牙统计局获取。

结论

过去16年社会人口统计学和生活方式的变化证明了EPISER 2016的合理性。本研究将提供有关RA、AS、PsA、SLE、SS、骨关节炎、纤维肌痛、痛风和临床骨质疏松性骨折患病率的当前数据。研究结果将有助于与其他国家的研究以及2000年的EPISER进行比较。

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