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偏倚风险评估:(3) 针对个体随机交叉试验的修订版Cochrane偏倚风险评估工具(RoB2.0)

[Bias risk assessment: (3) Revised Cochrane bias risk assessment tool for individual randomized, cross-over trials (RoB2.0)].

作者信息

Wu S S, Sun F, Zhan S Y

机构信息

National Clinical Research Center of Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Center of Evidence-Based Medicine and Clinical Research, Peking University, Beijing 100191, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Oct 10;38(10):1436-1440. doi: 10.3760/cma.j.issn.0254-6450.2017.10.028.

Abstract

This paper introduces the revised Cochrane bias risk assessment tool for individual randomized, cross-over trials (RoB2.0), comparing RoB2.0 of cross-over design with RoB2.0 of parallel design, and illustrating the application of RoB2.0 for cross-over trials in a published clinical trial. As a comprehensive tool specially designed for cross-over design, it provides more information on risk of bias in systematic reviews for the evidence synthesis.

摘要

本文介绍了针对个体随机交叉试验的修订版Cochrane偏倚风险评估工具(RoB2.0),比较了交叉设计的RoB2.0与平行设计的RoB2.0,并在一项已发表的临床试验中说明了RoB2.0在交叉试验中的应用。作为专门为交叉设计设计的综合工具,它为证据综合的系统评价提供了更多关于偏倚风险的信息。

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