神经性疼痛与睡眠：综述
Neuropathic Pain and Sleep: A Review.
作者信息
Ferini-Strambi Luigi
机构信息
Sleep Disorders Center, Department of Neurology, Scientific Institute Ospedale San Raffaele, Vita-Salute University, Milan, Italy.
出版信息
Pain Ther. 2017 Dec;6(Suppl 1):19-23. doi: 10.1007/s40122-017-0089-y. Epub 2017 Nov 24.
Abstract
UNLABELLED
Neuropathic pain is associated with sleep disturbances, and in turn poor sleep quality leads to increased pain sensitivity, so it is essential to assess sleep alongside neuropathic pain. Responses to drugs are inconsistent and identifying the best treatment option that will reduce pain and improve sleep quality remains challenging for clinicians. Anticonvulsants such as pregabalin and gabapentin improve neuropathic pain and have a positive effect on comorbid sleep disturbances. Opioids and antidepressants are effective in reducing pain but can exacerbate sleep disturbances.
FUNDING
Pfizer, Italy.
摘要
未标注
神经性疼痛与睡眠障碍相关，反过来，睡眠质量差会导致疼痛敏感性增加，因此在评估神经性疼痛的同时评估睡眠至关重要。药物反应不一致，确定能减轻疼痛并改善睡眠质量的最佳治疗方案对临床医生来说仍然具有挑战性。普瑞巴林和加巴喷丁等抗惊厥药可改善神经性疼痛，并对合并的睡眠障碍有积极作用。阿片类药物和抗抑郁药在减轻疼痛方面有效，但会加重睡眠障碍。
资助
意大利辉瑞公司。
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