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血管性痴呆的治疗。巴西神经病学学会认知神经病学与衰老科学部的建议。

Treatment of vascular dementia. Recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology.

作者信息

Brucki Sonia Maria Dozzi, Ferraz Ana Cláudia, de Freitas Gabriel R, Massaro Ayrton Roberto, Radanovic Márcia, Schultz Rodrigo Rizek

机构信息

Neurology Service, Hospital Santa Marcelina, Cognitive and Behavioral Neurology Group of Clínicas Hospital of the University of São Paulo School of Medicine (FMUSP), Referral Center for Cognitive Disorders (CEREDIC) of the FMUSP, São Paulo SP, Brazil.

D'Or Institute of Research and Teaching, University Federal Fluminense, Rio de Janeiro RJ, Brazil.

出版信息

Dement Neuropsychol. 2011 Oct-Dec;5(4):275-287. doi: 10.1590/S1980-57642011DN05040005.

Abstract

Scientific Department of Cognitive Neurology and Aging of ABN had a consensus meeting to write recommendations on treatment of vascular dementia, there was no previous issue. This disease has numerous particularities and can be considered a preventable dementia. Prevention treatment is primary care of vascular risk factors or a secondary prevention of factors that could cause recurrence of ischemic or hemorrhagic brain modifications. In these guidelines we suggested only symptomatic treatment, pharmacologic or non-pharmacologic. We have reviewed current publications on MEDLINE (PubMed), LILACS e Cochrane Library databases. Recommendations are concern to the following factors and their prevention evidences, association, or treatment of vascular dementia: physical activity, tobacco use, diet and food supplements, arterial hypertension, diabetes mellitus, obesity, statins, cardiac failure, atrial fibrillation, antithrombotics, sleep apnea, carotid revascularization, symptomatic pharmacological treatment.

摘要

ABN认知神经病学与衰老科学部召开了一次共识会议,以撰写关于血管性痴呆治疗的建议,此前没有相关问题。这种疾病有许多特殊性,可被视为一种可预防的痴呆症。预防治疗是对血管危险因素的初级护理,或是对可能导致缺血性或出血性脑改变复发的因素进行二级预防。在这些指南中,我们仅建议进行对症治疗,包括药物治疗或非药物治疗。我们检索了MEDLINE(PubMed)、LILACS和Cochrane图书馆数据库中的当前出版物。建议涉及以下因素及其预防证据、血管性痴呆的关联或治疗:体育活动、吸烟、饮食和食品补充剂、动脉高血压、糖尿病、肥胖、他汀类药物、心力衰竭、心房颤动、抗栓药物、睡眠呼吸暂停、颈动脉血运重建、对症药物治疗。

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