Department of Pediatrics, Nowon Eulji Medical Center, Eulji University, Seoul, 01830, Korea.
Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea.
Sci Rep. 2018 Jan 31;8(1):1962. doi: 10.1038/s41598-018-20274-8.
The present study aimed to describe the distribution of and to investigate the factors associated with glycated haemoglobin (HbA1c) values in Korean youth (10-19 years old) and young adults (20-29 years old). Data from the Korea Health and Nutrition Examination Survey (2011-2015) were used. A total of 6,418 participants (male 3,140 [53.2%]) aged 10-29 years were included in the analysis. Percentiles of HbA1c were calculated and HbA1c values were compared according to age, sex, and associated factors. The mean HbA1c values (% [mmol/mol]) were 5.42 ± 0.01 (35.7 ± 0.1) for youths and 5.32 ± 0.01 (34.7 ± 0.1) for young adults (P < 0.001). Male participants showed significantly higher HbA1c level than females (P < 0.001). When age was grouped into 5-year intervals, HbA1c was the highest in those aged 10-14 years and the lowest in those aged 20-24 years. After controlling for confounding variables, the HbA1c values of youths and male participants were significantly higher than those of young adults and female participants. The present study provides nationally representative data on the distribution of HbA1c values in Korean youth and young adults. There were significant differences in the level of HbA1c according to age and sex.
本研究旨在描述韩国青年(10-19 岁)和年轻成年人(20-29 岁)糖化血红蛋白(HbA1c)值的分布,并探讨其相关因素。本研究使用了 2011-2015 年韩国健康与营养调查的数据。共纳入了 6418 名 10-29 岁的参与者(男性 3140 名[53.2%])。计算了 HbA1c 的百分位数,并根据年龄、性别和相关因素比较了 HbA1c 值。青年和年轻成年人的平均 HbA1c 值(%[mmol/mol])分别为 5.42±0.01(35.7±0.1)和 5.32±0.01(34.7±0.1)(P<0.001)。男性参与者的 HbA1c 水平明显高于女性(P<0.001)。当年龄分为 5 年间隔时,10-14 岁年龄组的 HbA1c 最高,20-24 岁年龄组的 HbA1c 最低。在控制了混杂变量后,青年和男性参与者的 HbA1c 值明显高于年轻成年人和女性参与者。本研究提供了韩国青年和年轻成年人 HbA1c 值分布的全国代表性数据。HbA1c 水平根据年龄和性别存在显著差异。