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医源性创伤后三叉神经病变:一项为期两年的回顾性队列研究。

Iatrogenic trigeminal post-traumatic neuropathy: a retrospective two-year cohort study.

作者信息

Klazen Y, Van der Cruyssen F, Vranckx M, Van Vlierberghe M, Politis C, Renton T, Jacobs R

机构信息

OMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium; Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium.

OMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium; Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium.

出版信息

Int J Oral Maxillofac Surg. 2018 Jun;47(6):789-793. doi: 10.1016/j.ijom.2018.02.004. Epub 2018 Mar 6.

Abstract

With the growing demand for dental work, trigeminal nerve injuries are increasingly common. This retrospective cohort study examined 53 cases of iatrogenic trigeminal nerve injury seen at the Department of Oral and Maxillofacial Surgery, University Hospitals of Leuven between 2013 and 2014 (0.6% among 8845 new patient visits). Patient records were screened for post-traumatic trigeminal nerve neuropathy caused by nerve injury incurred during implant surgery, endodontic treatment, local anaesthesia, tooth extraction, or specifically third molar removal. The patients ranged in age from 15 to 80years (mean age 42.1years) and 68% were female. The referral delay ranged from 1day to 6.5years (average 10months). The inferior alveolar nerve (IAN) was most frequently injured (28 cases), followed by the lingual nerve (LN) (21 cases). Most nerve injuries were caused during third molar removal (24 cases), followed by implant placement (nine cases) and local anaesthesia injuries (nine cases). Pain symptoms were experienced by 54% of patients suffering IAN injury, compared to 10% of patients with LN injury. Persistent neurosensory disturbances were identified in 60% of patients. While prevention remains the key issue, timely referral seems to be a critical factor for the successful treatment of post-traumatic neuropathy.

摘要

随着牙科治疗需求的不断增加,三叉神经损伤日益常见。这项回顾性队列研究调查了2013年至2014年在鲁汶大学医院口腔颌面外科就诊的53例医源性三叉神经损伤病例(在8845例新患者就诊中占0.6%)。对患者记录进行筛查,以查找因种植手术、牙髓治疗、局部麻醉、拔牙或特别是拔除第三磨牙过程中发生的神经损伤导致的创伤后三叉神经神经病变。患者年龄在15岁至80岁之间(平均年龄42.1岁),68%为女性。转诊延迟时间从1天至6.5年不等(平均10个月)。下牙槽神经(IAN)最常受伤(28例),其次是舌神经(LN)(21例)。大多数神经损伤发生在拔除第三磨牙期间(24例),其次是种植体植入(9例)和局部麻醉损伤(9例)。IAN损伤患者中有54%出现疼痛症状,而LN损伤患者中这一比例为10%。60%的患者存在持续性神经感觉障碍。虽然预防仍然是关键问题,但及时转诊似乎是创伤后神经病变成功治疗的关键因素。

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