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Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer.

作者信息

Tan Shuangyan, Gou Qiheng, Pu Wenchen, Guo Chenglin, Yang Yun, Wu Ke, Liu Yaxin, Liu Lunxu, Wei Yu-Quan, Peng Yong

机构信息

Department of Thoracic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, 610041, Chengdu, China.

CAS Key Lab for Computational Biology, CAS Center for Excellence in Molecular Cell Science, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.

出版信息

Cell Res. 2018 Jun;28(6):693-695. doi: 10.1038/s41422-018-0033-7. Epub 2018 Apr 8.

Abstract
摘要

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本文引用的文献

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Non-small-cell lung cancer.
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Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.
Cell. 2016 Apr 7;165(2):289-302. doi: 10.1016/j.cell.2016.03.020. Epub 2016 Mar 31.
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The biogenesis and emerging roles of circular RNAs.
Nat Rev Mol Cell Biol. 2016 Apr;17(4):205-11. doi: 10.1038/nrm.2015.32. Epub 2016 Feb 24.
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Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.
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Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.
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EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.
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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.
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