结构分子生物学可视化的视角：从过去到现在。
Perspectives on Structural Molecular Biology Visualization: From Past to Present.
机构信息
Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
J Mol Biol. 2018 Oct 19;430(21):3997-4012. doi: 10.1016/j.jmb.2018.07.009. Epub 2018 Jul 23.
Abstract
Visualization has been a key technology in the progress of structural molecular biology for as long as the field has existed. This perspective describes the nature of the visualization process in structural studies, how it has evolved over the years, and its relationship to the changes in technology that have supported and driven it. It focuses on how technical advances have changed the way we look at and interact with molecular structure, and how structural biology has fostered and challenged that technology.
摘要
可视化技术一直是结构分子生物学发展的关键技术，只要该领域存在。本文从结构研究的角度描述了可视化过程的本质，探讨了它多年来的发展历程及其与支撑和推动它的技术变革的关系。本文重点介绍了技术进步如何改变了我们观察和与分子结构相互作用的方式，以及结构生物学如何促进和挑战这种技术。
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