Tang Wen-Xin, Zhang Lu-Feng, Ai Yan-Qiu, Li Zhi-Song
Department of Anaesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Medicine (Baltimore). 2018 Sep;97(36):e12061. doi: 10.1097/MD.0000000000012061.
Pediatric chronic pain is relatively common in the world. Although cognitive behavior therapy (CBT) has been shown to be efficacious in children and adolescents, it is generally recognized that availability and accessibility of CBT are limited. While Internet-delivered cognitive-behavioral therapy (ICBT) performs better in these areas.
This systematic review aims to evaluate the clinical effects of ICBT for chronic pain in youth when compared with the control treatments.
We searched electronic databases to identify randomized controlled trials that compared ICBT with the control therapy for pediatric chronic pain. The primary outcomes were 95% confidence intervals and mean difference or standardized mean difference in change of pain intensity and activity limitations.
Four trials met the inclusion criteria with a total of 404 participants of whom 208 received ICBT. Compared with pretreatment, children reported significant, medium to large benefits on pain intensity, activity limitations, and parental protective behaviors after receiving ICBT immediately. Significant small to medium effects were found for outcomes of depressive symptoms, anxiety, and sleep quality from baseline to post-treatment in the ICBT group. But most measures of ICBT did not show statistically significant superiority to those of the control conditions, except parental protective behaviors. Generally children and their parents were highly acceptable and satisfied with ICBT.
ICBT for physical and psychological conditions in youth with chronic pain is a full potential therapy; it can be successful on clinically effects and socioeconomic benefits. However, only limited data supported the conclusion, we require further methodologically robust trials.
PROSPERO CRD42017069811.
儿童慢性疼痛在全球较为常见。尽管认知行为疗法(CBT)已被证明对儿童和青少年有效,但人们普遍认识到CBT的可获得性和可及性有限。而互联网提供的认知行为疗法(ICBT)在这些方面表现更佳。
本系统评价旨在评估与对照治疗相比,ICBT治疗青少年慢性疼痛的临床效果。
我们检索电子数据库,以确定将ICBT与儿童慢性疼痛对照疗法进行比较的随机对照试验。主要结局指标为疼痛强度和活动受限变化的95%置信区间以及均值差或标准化均值差。
四项试验符合纳入标准,共有404名参与者,其中208人接受了ICBT。与治疗前相比,儿童在接受ICBT后立即报告在疼痛强度、活动受限和父母保护行为方面有显著的、中等到较大的改善。在ICBT组中,从基线到治疗后,抑郁症状、焦虑和睡眠质量的结局指标有显著的小到中等程度的改善。但除了父母保护行为外,ICBT的大多数指标在统计学上并未显示出优于对照条件的显著优势。总体而言,儿童及其父母对ICBT高度认可且满意。
ICBT治疗患有慢性疼痛的青少年的身心状况具有充分的潜力;它在临床效果和社会经济效益方面可能会取得成功。然而,仅有有限的数据支持这一结论,我们需要进一步进行方法学上更严谨的试验。
PROSPERO CRD42017069811