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有吸烟史的老年人在低剂量计算机断层扫描肺癌筛查资格方面的种族差异。

Racial disparities in eligibility for low-dose computed tomography lung cancer screening among older adults with a history of smoking.

作者信息

Li Chien-Ching, Matthews Alicia K, Rywant Mantle M, Hallgren Emily, Shah Raj C

机构信息

Department of Health Systems Management, Rush University, Chicago, IL, USA.

Department of Health Systems Science, University of Illinois at Chicago, Chicago, IL, USA.

出版信息

Cancer Causes Control. 2019 Mar;30(3):235-240. doi: 10.1007/s10552-018-1092-2. Epub 2018 Oct 30.

Abstract

PURPOSE

Lung cancer early detection screening has been demonstrated to decrease lung cancer mortality among high-risk smokers. This study aimed to examine whether current screening guidelines may disproportionately exclude African American smokers who are at higher overall risk for lung cancer.

METHODS

Data from the 2014 Health and Retirement Study were analyzed. Older African Americans and Whites with a history of smoking were included in the analyses (n = 7,348). Eligibility criteria established by the U.S. Preventive Services Task Force (USPSTF) for LDCT lung cancer screening were used. Multivariate logistic regression analyses were conducted to examine racial differences in eligibility for LDCT lung cancer screening.

RESULTS

Overall, 21.1% of current and 10.5% of former smokers met USPSTF's eligibility criteria for LDCT screening. In multivariate logistic regression analyses, African American smokers were less likely to be eligible for LDCT lung cancer screening compared to Whites (odds ratio = 0.5; p < 0.001).

CONCLUSION

African American smokers were less likely to meet established lung cancer screening eligibility criteria compared to Whites. Current lung cancer screening criteria may not adequately capture African Americans at risk and may widen the health disparities in African Americans. Further longitudinal studies are needed to evaluate the efficacy of current lung cancer screening guideline.

摘要

目的

肺癌早期检测筛查已被证明可降低高危吸烟者的肺癌死亡率。本研究旨在探讨当前的筛查指南是否可能不成比例地排除了肺癌总体风险较高的非裔美国吸烟者。

方法

分析了2014年健康与退休研究的数据。分析纳入了有吸烟史的老年非裔美国人和白人(n = 7348)。采用了美国预防服务工作组(USPSTF)制定的低剂量计算机断层扫描(LDCT)肺癌筛查资格标准。进行多因素逻辑回归分析以检查LDCT肺癌筛查资格的种族差异。

结果

总体而言,21.1%的当前吸烟者和10.5%的既往吸烟者符合USPSTF的LDCT筛查资格标准。在多因素逻辑回归分析中,与白人相比,非裔美国吸烟者符合LDCT肺癌筛查资格的可能性较小(优势比 = 0.5;p < 0.001)。

结论

与白人相比,非裔美国吸烟者符合既定肺癌筛查资格标准的可能性较小。当前的肺癌筛查标准可能无法充分涵盖有风险的非裔美国人,可能会扩大非裔美国人的健康差距。需要进一步的纵向研究来评估当前肺癌筛查指南的有效性。

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